Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM6 All Species: 24.55
Human Site: S802 Identified Species: 33.75
UniProt: Q14566 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14566 NP_005906.2 821 92889 S802 L K G S T E G S E S Y E E D P
Chimpanzee Pan troglodytes XP_001154613 821 92903 S802 L K G S T E G S E S Y E E D P
Rhesus Macaque Macaca mulatta XP_001096068 821 92830 S802 L K G S T E G S E S Y E E D P
Dog Lupus familis XP_533338 955 107181 S936 L K G S T E G S E S Y E E D P
Cat Felis silvestris
Mouse Mus musculus P97311 821 92849 S802 L K G S S E G S E S Y E E D P
Rat Rattus norvegicus Q62724 507 57351 E489 K G S S E G S E S Y E E D P Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510510 779 87819 G759 L R G A A D G G R E S Y E D D
Chicken Gallus gallus NP_001006527 916 103481 E807 L R G S K E E E T F D E D P Y
Frog Xenopus laevis Q7ZY18 825 93359 N806 L K G T E D E N V A K E E D P
Zebra Danio Brachydanio rerio XP_002662351 830 93777 S809 L K G S A E S S E T E S Q E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V461 817 92334 Q797 L K P R I Q V Q K D F V E E D
Honey Bee Apis mellifera XP_396515 813 91942 D794 T T D L R D K D E D E E D D P
Nematode Worm Caenorhab. elegans P34647 810 91112 E792 D H V L L E V E Q G E D P T L
Sea Urchin Strong. purpuratus XP_783166 823 93674 T797 L K T R R V G T P A V E G E E
Poplar Tree Populus trichocarpa
Maize Zea mays Q43704 768 85163 I748 T R S Q V E F I L E R M Q D A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P43299 716 80315 Y698 L K E C L E E Y A A L N V W Q
Baker's Yeast Sacchar. cerevisiae P53091 1017 112934 E990 N L R D L E N E E N E N N K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.7 83.8 N.A. 95.8 58.9 N.A. 84.7 78.5 82.6 80.9 N.A. 63.5 59.8 54.8 71.5
Protein Similarity: 100 100 100 84.7 N.A. 97.6 60.5 N.A. 89.7 84.8 91.1 89.2 N.A. 79 76.3 71.7 84.2
P-Site Identity: 100 100 100 100 N.A. 93.3 13.3 N.A. 33.3 33.3 46.6 46.6 N.A. 20 26.6 6.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 53.3 46.6 73.3 66.6 N.A. 46.6 40 20 46.6
Percent
Protein Identity: N.A. 26.4 N.A. 25.8 38.5 N.A.
Protein Similarity: N.A. 45.6 N.A. 44.7 56.5 N.A.
P-Site Identity: N.A. 13.3 N.A. 20 13.3 N.A.
P-Site Similarity: N.A. 26.6 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 12 0 0 0 6 18 0 0 0 0 6 % A
% Cys: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 6 6 0 18 0 6 0 12 6 6 18 53 12 % D
% Glu: 0 0 6 0 12 65 18 24 48 12 30 59 48 18 12 % E
% Phe: 0 0 0 0 0 0 6 0 0 6 6 0 0 0 0 % F
% Gly: 0 6 53 0 0 6 42 6 0 6 0 0 6 0 0 % G
% His: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 6 0 0 6 0 0 0 0 0 0 0 % I
% Lys: 6 59 0 0 6 0 6 0 6 0 6 0 0 6 0 % K
% Leu: 71 6 0 12 18 0 0 0 6 0 6 0 0 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % M
% Asn: 6 0 0 0 0 0 6 6 0 6 0 12 6 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 6 0 0 0 6 12 42 % P
% Gln: 0 0 0 6 0 6 0 6 6 0 0 0 12 0 6 % Q
% Arg: 0 18 6 12 12 0 0 0 6 0 6 0 0 0 0 % R
% Ser: 0 0 12 48 6 0 12 36 6 30 6 6 0 0 0 % S
% Thr: 12 6 6 6 24 0 0 6 6 6 0 0 0 6 6 % T
% Val: 0 0 6 0 6 6 12 0 6 0 6 6 6 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % W
% Tyr: 0 0 0 0 0 0 0 6 0 6 30 6 0 0 12 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _