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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
22.12
Human Site:
S804
Identified Species:
30.42
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
S804
G
S
T
E
G
S
E
S
Y
E
E
D
P
Y
L
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
S804
G
S
T
E
G
S
E
S
Y
E
E
D
P
Y
L
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
S804
G
S
T
E
G
S
E
S
Y
E
E
D
P
Y
L
Dog
Lupus familis
XP_533338
955
107181
S938
G
S
T
E
G
S
E
S
Y
E
E
D
P
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
S804
G
S
S
E
G
S
E
S
Y
E
E
D
P
Y
L
Rat
Rattus norvegicus
Q62724
507
57351
Y491
S
S
E
G
S
E
S
Y
E
E
D
P
Y
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
E761
G
A
A
D
G
G
R
E
S
Y
E
D
D
P
Y
Chicken
Gallus gallus
NP_001006527
916
103481
F809
G
S
K
E
E
E
T
F
D
E
D
P
Y
L
V
Frog
Xenopus laevis
Q7ZY18
825
93359
A808
G
T
E
D
E
N
V
A
K
E
E
D
P
Y
L
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
T811
G
S
A
E
S
S
E
T
E
S
Q
E
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
D799
P
R
I
Q
V
Q
K
D
F
V
E
E
D
D
P
Honey Bee
Apis mellifera
XP_396515
813
91942
D796
D
L
R
D
K
D
E
D
E
E
D
D
P
L
L
Nematode Worm
Caenorhab. elegans
P34647
810
91112
G794
V
L
L
E
V
E
Q
G
E
D
P
T
L
C
V
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
A799
T
R
R
V
G
T
P
A
V
E
G
E
E
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
E750
S
Q
V
E
F
I
L
E
R
M
Q
D
A
N
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
A700
E
C
L
E
E
Y
A
A
L
N
V
W
Q
I
D
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
N992
R
D
L
E
N
E
E
N
E
N
N
K
T
V
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
26.6
26.6
46.6
33.3
N.A.
6.6
33.3
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
40
40
73.3
60
N.A.
33.3
46.6
26.6
40
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
12
0
0
0
6
18
0
0
0
0
6
0
0
% A
% Cys:
0
6
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
6
6
0
18
0
6
0
12
6
6
18
53
12
12
6
% D
% Glu:
6
0
12
65
18
24
48
12
30
59
48
18
12
0
0
% E
% Phe:
0
0
0
0
6
0
0
6
6
0
0
0
0
0
0
% F
% Gly:
53
0
0
6
42
6
0
6
0
0
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
0
6
0
0
0
0
0
0
0
6
0
% I
% Lys:
0
0
6
0
6
0
6
0
6
0
0
6
0
0
0
% K
% Leu:
0
12
18
0
0
0
6
0
6
0
0
0
6
18
42
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
0
0
6
0
% M
% Asn:
0
0
0
0
6
6
0
6
0
12
6
0
0
6
0
% N
% Pro:
6
0
0
0
0
0
6
0
0
0
6
12
42
6
6
% P
% Gln:
0
6
0
6
0
6
6
0
0
0
12
0
6
0
0
% Q
% Arg:
6
12
12
0
0
0
6
0
6
0
0
0
0
0
6
% R
% Ser:
12
48
6
0
12
36
6
30
6
6
0
0
0
0
0
% S
% Thr:
6
6
24
0
0
6
6
6
0
0
0
6
6
0
0
% T
% Val:
6
0
6
6
12
0
6
0
6
6
6
0
0
6
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% W
% Tyr:
0
0
0
0
0
6
0
6
30
6
0
0
12
36
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _