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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
37.27
Human Site:
T195
Identified Species:
51.25
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
T195
R
R
R
F
L
L
D
T
N
K
S
R
F
V
D
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
T195
R
R
R
F
L
L
D
T
N
K
S
R
F
V
D
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
T195
R
R
R
F
L
L
D
T
N
K
S
R
F
V
D
Dog
Lupus familis
XP_533338
955
107181
T329
R
R
R
F
L
L
D
T
N
K
S
R
F
V
D
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
T195
R
K
R
F
L
L
D
T
N
K
S
R
F
V
D
Rat
Rattus norvegicus
Q62724
507
57351
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
I181
I
P
R
S
L
E
V
I
L
R
A
E
A
V
E
Chicken
Gallus gallus
NP_001006527
916
103481
T196
R
R
R
F
L
L
D
T
N
K
S
R
F
V
D
Frog
Xenopus laevis
Q7ZY18
825
93359
T196
R
K
R
F
M
L
D
T
N
K
S
R
F
V
D
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
T193
R
R
R
F
L
L
D
T
N
K
S
K
F
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
L187
S
N
R
K
R
F
M
L
D
V
E
K
S
L
F
Honey Bee
Apis mellifera
XP_396515
813
91942
V189
R
R
R
F
L
L
D
V
D
N
S
I
F
I
D
Nematode Worm
Caenorhab. elegans
P34647
810
91112
V194
R
T
R
F
S
L
D
V
N
S
S
T
F
V
D
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
T189
R
S
R
F
M
L
D
T
N
K
S
R
F
V
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
Y184
G
N
L
L
V
T
E
Y
G
M
C
E
Y
K
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
I157
H
I
G
Q
L
V
R
I
S
G
I
V
T
R
C
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
V348
R
A
F
W
T
L
N
V
T
R
S
R
F
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
20
100
86.6
86.6
N.A.
6.6
66.6
66.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
40
100
100
100
N.A.
26.6
80
66.6
93.3
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
40
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
0
0
0
6
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
6
% C
% Asp:
0
0
0
0
0
0
65
0
12
0
0
0
0
0
77
% D
% Glu:
0
0
0
0
0
6
6
0
0
0
6
12
0
0
6
% E
% Phe:
0
0
6
65
0
6
0
0
0
0
0
0
71
0
6
% F
% Gly:
6
0
6
0
0
0
0
0
6
6
0
0
0
0
0
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
0
0
0
0
0
12
0
0
6
6
0
12
0
% I
% Lys:
0
12
0
6
0
0
0
0
0
53
0
12
0
6
0
% K
% Leu:
0
0
6
6
59
71
0
6
6
0
0
0
0
12
0
% L
% Met:
0
0
0
0
12
0
6
0
0
6
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
6
0
59
6
0
0
0
0
0
% N
% Pro:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
71
42
77
0
6
0
6
0
0
12
0
53
0
6
0
% R
% Ser:
6
6
0
6
6
0
0
0
6
6
71
0
6
0
0
% S
% Thr:
0
6
0
0
6
6
0
53
6
0
0
6
6
0
0
% T
% Val:
0
0
0
0
6
6
6
18
0
6
0
6
0
59
0
% V
% Trp:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
6
0
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _