KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
39.09
Human Site:
T321
Identified Species:
53.75
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
T321
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
T321
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
T321
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Dog
Lupus familis
XP_533338
955
107181
T455
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
T321
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Rat
Rattus norvegicus
Q62724
507
57351
G74
G
E
G
T
S
L
R
G
D
I
N
V
C
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
S307
L
Y
H
N
L
C
T
S
L
F
P
T
I
H
G
Chicken
Gallus gallus
NP_001006527
916
103481
T322
E
L
R
D
E
E
Q
T
A
E
S
I
K
N
Q
Frog
Xenopus laevis
Q7ZY18
825
93359
T322
D
L
H
E
E
D
M
T
A
E
S
I
K
N
Q
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
T319
E
I
R
D
E
E
Q
T
A
E
S
I
K
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
T313
D
L
P
M
S
E
V
T
A
E
D
M
K
K
Q
Honey Bee
Apis mellifera
XP_396515
813
91942
Q315
T
N
M
E
E
L
S
Q
E
M
M
K
K
R
M
Nematode Worm
Caenorhab. elegans
P34647
810
91112
T320
A
S
G
A
V
E
E
T
D
Y
L
D
L
W
S
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
T315
D
M
R
G
E
E
M
T
A
E
A
I
K
K
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
K310
Y
G
H
L
W
I
K
K
A
V
V
L
L
M
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
R283
Y
T
G
F
K
A
L
R
A
G
L
V
A
D
T
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
N474
G
A
S
S
P
D
A
N
S
N
N
R
E
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
100
66.6
86.6
N.A.
46.6
13.3
13.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
100
86.6
93.3
N.A.
60
20
20
80
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
0
6
6
0
71
0
6
0
6
0
0
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
6
0
0
% C
% Asp:
18
0
0
42
0
12
0
0
12
0
6
6
0
6
0
% D
% Glu:
42
6
0
12
59
59
6
0
6
59
0
0
6
0
6
% E
% Phe:
0
0
0
6
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
12
6
18
6
0
0
0
6
0
6
0
0
0
0
6
% G
% His:
0
0
18
0
0
0
0
0
0
0
0
0
0
6
0
% H
% Ile:
0
6
0
0
0
6
0
0
0
6
0
53
6
6
0
% I
% Lys:
0
0
0
0
6
0
6
6
0
0
0
6
65
18
0
% K
% Leu:
6
48
0
6
6
12
6
0
6
0
12
6
12
0
6
% L
% Met:
0
6
6
6
0
0
12
0
0
6
6
6
0
6
6
% M
% Asn:
0
6
0
6
0
0
0
6
0
6
12
0
0
42
0
% N
% Pro:
0
0
6
0
6
0
0
0
0
0
6
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
42
6
0
0
0
0
0
0
59
% Q
% Arg:
0
0
48
0
0
0
6
6
0
0
0
6
0
6
0
% R
% Ser:
0
6
6
6
12
0
6
6
6
0
48
0
0
0
6
% S
% Thr:
6
6
0
6
0
0
6
65
0
0
0
6
0
6
6
% T
% Val:
0
0
0
0
6
0
6
0
0
6
6
12
0
0
6
% V
% Trp:
0
0
0
0
6
0
0
0
0
0
0
0
0
6
0
% W
% Tyr:
12
6
0
0
0
0
0
0
0
6
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _