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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
46.97
Human Site:
T380
Identified Species:
64.58
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
T380
F
G
G
V
P
K
T
T
G
E
G
T
S
L
R
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
T380
F
G
G
V
P
K
T
T
G
E
G
T
S
L
R
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
T380
F
G
G
V
P
K
T
T
G
E
G
T
S
L
R
Dog
Lupus familis
XP_533338
955
107181
T514
F
G
G
V
P
K
T
T
G
E
G
T
S
L
R
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
T380
F
G
G
V
P
K
T
T
G
E
G
T
S
L
R
Rat
Rattus norvegicus
Q62724
507
57351
H126
V
V
R
D
E
E
S
H
E
F
V
I
E
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
F359
P
S
T
A
K
S
Q
F
L
K
H
V
E
E
F
Chicken
Gallus gallus
NP_001006527
916
103481
T381
F
G
G
V
P
K
T
T
S
E
G
T
S
L
R
Frog
Xenopus laevis
Q7ZY18
825
93359
T381
F
G
G
V
P
K
S
T
M
E
G
T
S
L
R
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
T378
F
G
G
V
P
K
T
T
M
E
G
T
S
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
T372
F
G
G
V
A
K
T
T
T
E
K
T
S
L
R
Honey Bee
Apis mellifera
XP_396515
813
91942
T373
F
G
G
V
P
K
T
T
M
E
G
T
S
L
R
Nematode Worm
Caenorhab. elegans
P34647
810
91112
R381
G
G
V
A
K
K
S
R
D
E
G
T
S
L
R
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
T374
F
G
G
V
P
K
T
T
M
E
K
T
S
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
T363
I
A
P
L
A
I
S
T
T
G
R
G
S
S
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
A335
N
K
L
S
R
S
L
A
P
E
I
Y
G
H
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
T559
L
G
G
V
H
K
S
T
V
E
G
I
K
L
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
93.3
86.6
93.3
N.A.
80
93.3
53.3
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
93.3
93.3
93.3
N.A.
80
93.3
60
86.6
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
60
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
6.6
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
12
12
0
0
6
0
0
0
0
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
6
6
0
0
6
83
0
0
12
6
6
% E
% Phe:
65
0
0
0
0
0
0
6
0
6
0
0
0
0
6
% F
% Gly:
6
77
71
0
0
0
0
0
30
6
65
6
6
0
12
% G
% His:
0
0
0
0
6
0
0
6
0
0
6
0
0
6
0
% H
% Ile:
6
0
0
0
0
6
0
0
0
0
6
12
0
0
0
% I
% Lys:
0
6
0
0
12
77
0
0
0
6
12
0
6
0
0
% K
% Leu:
6
0
6
6
0
0
6
0
6
0
0
0
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
6
0
6
0
59
0
0
0
6
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
6
0
6
0
0
6
0
0
6
0
0
0
77
% R
% Ser:
0
6
0
6
0
12
30
0
6
0
0
0
77
6
0
% S
% Thr:
0
0
6
0
0
0
59
77
12
0
0
71
0
0
0
% T
% Val:
6
6
6
71
0
0
0
0
6
0
6
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _