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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
30
Human Site:
T791
Identified Species:
41.25
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
T791
D
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
T791
D
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
T791
D
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
Dog
Lupus familis
XP_533338
955
107181
T925
D
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
T791
D
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
Rat
Rattus norvegicus
Q62724
507
57351
Q478
H
V
L
I
E
L
T
Q
A
G
L
K
G
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
T748
D
H
V
L
I
E
L
T
Q
A
G
L
R
G
A
Chicken
Gallus gallus
NP_001006527
916
103481
S796
D
H
I
L
I
E
L
S
Q
S
G
L
R
G
S
Frog
Xenopus laevis
Q7ZY18
825
93359
I795
D
Q
I
L
I
E
L
I
Q
T
G
L
K
G
T
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
K798
D
Y
I
L
I
E
L
K
Q
S
G
L
K
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
K786
D
Q
V
I
I
P
L
K
T
S
T
L
K
P
R
Honey Bee
Apis mellifera
XP_396515
813
91942
I783
T
Y
H
D
Q
I
I
I
P
L
T
T
T
D
L
Nematode Worm
Caenorhab. elegans
P34647
810
91112
L781
C
E
R
V
I
H
R
L
I
H
Q
D
H
V
L
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
A786
D
H
V
I
I
E
L
A
K
T
G
L
K
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
T737
Q
M
V
N
R
E
S
T
A
P
Y
T
R
S
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
S687
W
I
S
R
K
G
Y
S
E
A
Q
L
K
E
C
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
G979
R
I
L
M
E
I
H
G
T
R
H
N
L
R
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
86.6
73.3
66.6
73.3
N.A.
40
0
6.6
60
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
100
80
93.3
N.A.
53.3
13.3
13.3
73.3
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
20
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
6
12
42
0
0
0
0
6
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
65
0
0
6
0
0
0
0
0
0
0
6
0
6
6
% D
% Glu:
0
6
0
0
12
65
0
0
6
0
0
0
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
6
0
6
0
6
59
0
6
53
0
% G
% His:
6
48
6
0
0
6
6
0
0
6
6
0
6
0
0
% H
% Ile:
0
12
18
18
71
12
6
12
6
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
6
0
0
12
6
0
0
6
59
0
0
% K
% Leu:
0
0
12
53
0
6
65
6
0
6
6
71
6
0
12
% L
% Met:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
6
6
0
0
0
6
0
% P
% Gln:
6
12
0
0
6
0
0
6
53
0
12
0
0
0
6
% Q
% Arg:
6
0
6
6
6
0
6
0
0
6
0
0
18
6
12
% R
% Ser:
0
0
6
0
0
0
6
12
0
18
0
0
0
12
48
% S
% Thr:
6
0
0
0
0
0
6
42
12
12
12
12
6
6
6
% T
% Val:
0
6
53
6
0
0
0
0
0
0
0
0
0
6
0
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
6
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _