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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
30.3
Human Site:
Y276
Identified Species:
41.67
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
Y276
R
V
S
G
V
D
G
Y
E
T
E
G
I
R
G
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
Y276
R
V
S
G
V
D
G
Y
E
T
E
G
I
R
G
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
Y276
R
V
S
G
V
D
G
Y
E
T
E
G
I
R
G
Dog
Lupus familis
XP_533338
955
107181
Y410
R
V
S
G
V
D
G
Y
E
T
E
G
I
R
G
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
Y276
R
V
S
G
A
D
G
Y
E
T
E
G
I
R
G
Rat
Rattus norvegicus
Q62724
507
57351
D29
K
V
F
E
M
S
Q
D
Q
N
L
Y
H
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
P262
C
Y
V
A
P
T
N
P
R
F
G
G
K
E
L
Chicken
Gallus gallus
NP_001006527
916
103481
Y277
R
V
S
G
T
E
G
Y
E
T
E
G
I
R
G
Frog
Xenopus laevis
Q7ZY18
825
93359
Y277
R
V
G
G
R
E
G
Y
E
A
E
G
V
Q
G
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
Y274
R
T
A
G
V
Q
G
Y
E
N
E
G
L
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
E268
S
S
R
H
K
P
G
E
G
M
D
G
V
T
G
Honey Bee
Apis mellifera
XP_396515
813
91942
D270
K
R
R
K
T
A
E
D
G
D
G
I
T
G
L
Nematode Worm
Caenorhab. elegans
P34647
810
91112
D275
Q
N
R
G
R
A
T
D
K
S
E
G
I
T
G
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
F270
R
G
K
G
G
A
G
F
D
Q
E
G
V
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
N265
A
N
N
V
S
L
L
N
K
E
A
N
A
P
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
V238
M
Q
E
L
A
E
H
V
P
K
G
H
I
P
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
T429
D
T
R
G
I
S
K
T
T
E
G
L
N
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
6.6
86.6
60
66.6
N.A.
20
0
33.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
26.6
N.A.
6.6
93.3
80
80
N.A.
33.3
6.6
53.3
66.6
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
0
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
6
12
18
0
0
0
6
6
0
6
0
0
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
30
0
18
6
6
6
0
0
0
0
% D
% Glu:
0
0
6
6
0
18
6
6
48
12
59
0
0
6
0
% E
% Phe:
0
0
6
0
0
0
0
6
0
6
0
0
0
0
0
% F
% Gly:
0
6
6
65
6
0
59
0
12
0
24
71
0
6
71
% G
% His:
0
0
0
6
0
0
6
0
0
0
0
6
6
0
0
% H
% Ile:
0
0
0
0
6
0
0
0
0
0
0
6
48
0
0
% I
% Lys:
12
0
6
6
6
0
6
0
12
6
0
0
6
0
0
% K
% Leu:
0
0
0
6
0
6
6
0
0
0
6
6
6
0
18
% L
% Met:
6
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
12
6
0
0
0
6
6
0
12
0
6
6
6
0
% N
% Pro:
0
0
0
0
6
6
0
6
6
0
0
0
0
12
0
% P
% Gln:
6
6
0
0
0
6
6
0
6
6
0
0
0
6
0
% Q
% Arg:
53
6
24
0
12
0
0
0
6
0
0
0
0
48
6
% R
% Ser:
6
6
36
0
6
12
0
0
0
6
0
0
0
6
0
% S
% Thr:
0
12
0
0
12
6
6
6
6
36
0
0
6
12
0
% T
% Val:
0
48
6
6
30
0
0
6
0
0
0
0
18
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
48
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _