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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM6
All Species:
39.39
Human Site:
Y46
Identified Species:
54.17
UniProt:
Q14566
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14566
NP_005906.2
821
92889
Y46
S
S
D
G
E
I
K
Y
L
Q
L
A
E
E
L
Chimpanzee
Pan troglodytes
XP_001154613
821
92903
Y46
S
S
D
G
E
I
K
Y
L
Q
L
A
E
E
L
Rhesus Macaque
Macaca mulatta
XP_001096068
821
92830
Y46
S
S
D
G
E
V
K
Y
L
Q
L
A
E
E
L
Dog
Lupus familis
XP_533338
955
107181
Y180
N
S
D
G
E
I
K
Y
L
Q
L
A
E
E
L
Cat
Felis silvestris
Mouse
Mus musculus
P97311
821
92849
Y46
G
S
D
G
E
I
K
Y
L
Q
F
A
E
E
L
Rat
Rattus norvegicus
Q62724
507
57351
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510510
779
87819
P37
C
R
E
V
R
G
V
P
G
W
V
Y
P
Y
L
Chicken
Gallus gallus
NP_001006527
916
103481
Y47
N
C
D
G
E
V
K
Y
L
R
D
A
E
E
L
Frog
Xenopus laevis
Q7ZY18
825
93359
Y47
G
S
D
G
E
L
K
Y
Q
S
D
A
E
E
L
Zebra Danio
Brachydanio rerio
XP_002662351
830
93777
Y44
N
S
D
G
E
V
K
Y
L
R
D
A
E
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V461
817
92334
Y40
K
E
D
G
E
I
K
Y
T
R
P
A
A
S
L
Honey Bee
Apis mellifera
XP_396515
813
91942
Y40
K
E
D
G
V
V
K
Y
L
E
P
A
K
E
L
Nematode Worm
Caenorhab. elegans
P34647
810
91112
K45
F
I
Y
K
S
A
M
K
E
L
V
Q
P
E
K
Sea Urchin
Strong. purpuratus
XP_783166
823
93674
Y40
T
V
D
D
D
V
K
Y
L
R
D
V
Q
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q43704
768
85163
R40
R
D
M
V
Q
N
K
R
H
R
L
I
I
G
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P43299
716
80315
A13
F
D
G
D
K
G
L
A
K
G
F
L
E
N
F
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
T199
Y
A
P
E
L
L
N
T
S
D
S
L
K
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.7
83.8
N.A.
95.8
58.9
N.A.
84.7
78.5
82.6
80.9
N.A.
63.5
59.8
54.8
71.5
Protein Similarity:
100
100
100
84.7
N.A.
97.6
60.5
N.A.
89.7
84.8
91.1
89.2
N.A.
79
76.3
71.7
84.2
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
0
N.A.
6.6
66.6
66.6
73.3
N.A.
53.3
53.3
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
86.6
0
N.A.
20
86.6
73.3
93.3
N.A.
60
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
26.4
N.A.
25.8
38.5
N.A.
Protein Similarity:
N.A.
45.6
N.A.
44.7
56.5
N.A.
P-Site Identity:
N.A.
13.3
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
6
0
6
0
0
0
59
6
0
0
% A
% Cys:
6
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
65
12
6
0
0
0
0
6
24
0
0
0
0
% D
% Glu:
0
12
6
6
53
0
0
0
6
6
0
0
53
65
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
6
% F
% Gly:
12
0
6
59
0
12
0
0
6
6
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% H
% Ile:
0
6
0
0
0
30
0
0
0
0
0
6
6
0
0
% I
% Lys:
12
0
0
6
6
0
71
6
6
0
0
0
12
0
6
% K
% Leu:
0
0
0
0
6
12
6
0
53
6
30
12
0
0
71
% L
% Met:
0
0
6
0
0
0
6
0
0
0
0
0
0
0
6
% M
% Asn:
18
0
0
0
0
6
6
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
6
0
0
0
0
6
0
0
12
0
12
0
0
% P
% Gln:
0
0
0
0
6
0
0
0
6
30
0
6
6
0
0
% Q
% Arg:
6
6
0
0
6
0
0
6
0
30
0
0
0
6
0
% R
% Ser:
18
42
0
0
6
0
0
0
6
6
6
0
0
6
6
% S
% Thr:
6
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% T
% Val:
0
6
0
12
6
30
6
0
0
0
12
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
6
0
6
0
0
0
0
65
0
0
0
6
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _