KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AA2
All Species:
32.62
Human Site:
T7
Identified Species:
55.2
UniProt:
Q14568
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14568
NP_005339
343
39365
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Chimpanzee
Pan troglodytes
A5A6K9
733
84754
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Rhesus Macaque
Macaca mulatta
XP_001098426
696
80269
E231
E
I
S
D
D
E
A
E
E
E
K
G
E
K
E
Dog
Lupus familis
XP_848783
483
56243
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P07901
733
84769
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Rat
Rattus norvegicus
P82995
733
84796
T7
_
M
P
E
E
T
Q
T
Q
D
Q
P
M
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512830
733
84847
T7
_
M
P
E
E
M
Q
T
Q
D
H
S
M
E
E
Chicken
Gallus gallus
P11501
728
84041
T7
_
M
P
E
A
V
Q
T
Q
D
Q
P
M
E
E
Frog
Xenopus laevis
NP_001085598
729
84174
A8
M
P
D
E
V
Q
T
A
T
Q
E
Q
Q
M
E
Zebra Danio
Brachydanio rerio
Q90474
725
83300
T62
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
T53
K
I
R
Y
E
S
L
T
D
P
S
K
L
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
Y26
S
L
I
I
N
T
F
Y
S
N
K
E
I
Y
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55737
699
80046
K243
E
V
D
E
E
K
E
K
E
E
K
K
K
K
K
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
S51
K
I
R
Y
Q
A
L
S
D
P
K
Q
L
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
45
39.6
67.6
N.A.
44.8
45
N.A.
42.9
40.5
39.3
36.9
N.A.
36.8
N.A.
34.1
N.A.
Protein Similarity:
100
45.5
44.4
68.9
N.A.
45.5
45.5
N.A.
44.7
43.1
42.7
43
N.A.
41.4
N.A.
41.3
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
78.5
85.7
13.3
13.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
53.3
100
N.A.
100
100
N.A.
78.5
85.7
20
40
N.A.
40
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.4
31.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
8
8
0
0
0
22
50
0
0
0
15
0
% D
% Glu:
15
0
0
65
65
8
8
8
15
15
8
8
8
58
65
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
29
8
8
0
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
22
0
0
0
0
8
0
8
0
0
29
22
8
15
8
% K
% Leu:
0
8
0
0
0
0
22
0
0
0
0
0
22
0
8
% L
% Met:
8
50
0
0
0
8
0
0
0
0
0
0
50
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
50
0
0
0
0
0
0
22
0
43
0
0
0
% P
% Gln:
0
0
0
0
8
8
50
0
50
8
43
15
8
0
0
% Q
% Arg:
0
0
22
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
0
8
0
0
15
0
8
8
0
15
8
0
0
15
% S
% Thr:
0
0
0
0
0
43
8
65
8
0
0
0
0
0
8
% T
% Val:
0
8
0
0
8
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
22
0
0
0
8
0
0
0
0
0
8
0
% Y
% Spaces:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _