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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPR2
All Species:
26.67
Human Site:
S118
Identified Species:
65.19
UniProt:
Q14571
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14571
NP_002214.2
2701
308064
S118
L
G
E
I
V
K
Y
S
N
V
I
Q
L
L
H
Chimpanzee
Pan troglodytes
XP_518409
2650
301859
G119
H
G
D
V
V
K
Y
G
S
V
I
Q
L
L
H
Rhesus Macaque
Macaca mulatta
XP_001102937
2700
308048
S118
L
G
E
I
V
K
Y
S
N
V
I
Q
L
L
H
Dog
Lupus familis
XP_852399
2701
308021
S118
L
G
E
I
V
K
Y
S
N
V
I
Q
L
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z329
2701
307428
S118
L
G
E
I
V
K
Y
S
N
V
I
Q
L
L
H
Rat
Rattus norvegicus
P29995
2701
307040
S118
L
G
E
I
V
K
Y
S
K
V
I
Q
L
L
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235613
2701
307518
S120
L
G
E
I
V
K
Y
S
N
V
I
Q
L
L
H
Frog
Xenopus laevis
NP_001084015
2693
306654
G118
L
G
T
V
I
Q
Y
G
N
V
I
Q
L
L
H
Zebra Danio
Brachydanio rerio
XP_691057
2588
295620
S118
L
G
E
V
V
K
Y
S
R
V
I
Q
L
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29993
2838
319089
R122
G
T
S
I
Q
Y
G
R
A
V
V
Q
L
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.5
99.4
97.8
N.A.
95.7
95.3
N.A.
N.A.
92
69.1
72.7
N.A.
55.2
N.A.
N.A.
N.A.
Protein Similarity:
100
76.3
99.7
98.9
N.A.
98
97.6
N.A.
N.A.
95.3
81.9
82.8
N.A.
70.2
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
100
N.A.
100
93.3
N.A.
N.A.
100
66.6
86.6
N.A.
40
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
93.3
N.A.
N.A.
100
86.6
93.3
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
90
0
0
0
0
10
20
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% H
% Ile:
0
0
0
70
10
0
0
0
0
0
90
0
0
0
0
% I
% Lys:
0
0
0
0
0
80
0
0
10
0
0
0
0
0
0
% K
% Leu:
80
0
0
0
0
0
0
0
0
0
0
0
100
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
10
0
0
0
0
0
100
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
70
10
0
0
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
30
80
0
0
0
0
100
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
90
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _