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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR2 All Species: 22.73
Human Site: Y546 Identified Species: 55.56
UniProt: Q14571 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14571 NP_002214.2 2701 308064 Y546 E D L G D Q R Y A P Y K Y M L
Chimpanzee Pan troglodytes XP_518409 2650 301859 N540 E E L S D Q K N A P Y Q H M F
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 Y545 E D L G D Q R Y A P Y K Y M L
Dog Lupus familis XP_852399 2701 308021 Y546 E D L G D Q R Y A P Y K Y M L
Cat Felis silvestris
Mouse Mus musculus Q9Z329 2701 307428 Y546 E D L G D Q R Y A P Y K Y V L
Rat Rattus norvegicus P29995 2701 307040 Y546 E D L G D Q R Y A P Y K Y V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235613 2701 307518 Y547 E D L G D Q R Y A P Y K Y M L
Frog Xenopus laevis NP_001084015 2693 306654 H531 E E L G D Q R H A P F R H I C
Zebra Danio Brachydanio rerio XP_691057 2588 295620 N519 Q K L M R E Q N I L A Q I F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 N570 D E L S D P K N S P Y K N I F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.5 99.4 97.8 N.A. 95.7 95.3 N.A. N.A. 92 69.1 72.7 N.A. 55.2 N.A. N.A. N.A.
Protein Similarity: 100 76.3 99.7 98.9 N.A. 98 97.6 N.A. N.A. 95.3 81.9 82.8 N.A. 70.2 N.A. N.A. N.A.
P-Site Identity: 100 53.3 100 100 N.A. 93.3 93.3 N.A. N.A. 100 53.3 6.6 N.A. 33.3 N.A. N.A. N.A.
P-Site Similarity: 100 80 100 100 N.A. 100 100 N.A. N.A. 100 93.3 33.3 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 80 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 10 60 0 0 90 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 80 30 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 10 0 0 10 20 % F
% Gly: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 20 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 10 20 0 % I
% Lys: 0 10 0 0 0 0 20 0 0 0 0 70 0 0 0 % K
% Leu: 0 0 100 0 0 0 0 0 0 10 0 0 0 0 60 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 0 0 30 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 90 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 80 10 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 0 0 10 0 70 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 20 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 60 0 0 80 0 60 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _