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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPR3
All Species:
16.67
Human Site:
S2450
Identified Species:
45.83
UniProt:
Q14573
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14573
NP_002215.2
2671
304106
S2450
E
E
D
R
E
L
D
S
T
E
R
A
C
D
T
Chimpanzee
Pan troglodytes
XP_518409
2650
301859
S2429
E
E
D
R
E
L
D
S
T
E
R
A
C
D
T
Rhesus Macaque
Macaca mulatta
XP_001102937
2700
308048
G2473
A
D
E
E
Y
E
D
G
I
E
R
T
C
D
T
Dog
Lupus familis
XP_538867
2647
301264
S2426
E
G
N
E
E
L
E
S
T
E
R
A
C
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P70227
2670
304256
S2449
E
E
D
E
E
P
D
S
T
E
R
A
C
D
T
Rat
Rattus norvegicus
Q63269
2670
304268
S2449
E
E
D
E
E
L
D
S
T
E
R
A
C
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418035
2664
304757
A2447
D
T
D
Q
W
E
R
A
C
D
T
L
L
M
C
Frog
Xenopus laevis
NP_001084015
2693
306654
E2466
V
T
E
E
E
E
E
E
K
E
H
T
C
E
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29993
2838
319089
V2614
P
S
A
G
G
G
E
V
K
E
R
S
C
D
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.8
65.2
95.7
N.A.
95.3
95.2
N.A.
N.A.
89.7
62.9
N.A.
N.A.
51.7
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
77.8
97
N.A.
97.6
97.4
N.A.
N.A.
94.5
77.6
N.A.
N.A.
68.1
N.A.
N.A.
N.A.
P-Site Identity:
100
100
40
73.3
N.A.
86.6
93.3
N.A.
N.A.
6.6
26.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
86.6
N.A.
86.6
93.3
N.A.
N.A.
33.3
46.6
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
0
12
0
0
0
56
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
89
0
12
% C
% Asp:
12
12
56
0
0
0
56
0
0
12
0
0
0
78
0
% D
% Glu:
56
45
23
56
67
34
34
12
0
89
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
12
0
12
12
12
0
12
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
45
0
0
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% M
% Asn:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
23
0
0
12
0
0
0
78
0
0
0
0
% R
% Ser:
0
12
0
0
0
0
0
56
0
0
0
12
0
0
12
% S
% Thr:
0
23
0
0
0
0
0
0
56
0
12
23
0
0
78
% T
% Val:
12
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _