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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPR3 All Species: 12.42
Human Site: S328 Identified Species: 34.17
UniProt: Q14573 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14573 NP_002215.2 2671 304106 S328 P S Y K G D A S D P K A A G M
Chimpanzee Pan troglodytes XP_518409 2650 301859 S322 P S Y K G D T S D P K A A G M
Rhesus Macaque Macaca mulatta XP_001102937 2700 308048 N327 P D Y R D A Q N E G K N V R D
Dog Lupus familis XP_538867 2647 301264 C304 P S Y K G D V C E P K A A G M
Cat Felis silvestris
Mouse Mus musculus P70227 2670 304256 S328 P S Y K G D V S D P K A A G L
Rat Rattus norvegicus Q63269 2670 304268 S328 P S Y K G D V S D P K A A G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418035 2664 304757 A328 P S Y K G D V A E P K A A P T
Frog Xenopus laevis NP_001084015 2693 306654 L314 H L A T G H Y L A A E I D A E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P29993 2838 319089 C349 H D L H L G D C S K D S G L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 65.2 95.7 N.A. 95.3 95.2 N.A. N.A. 89.7 62.9 N.A. N.A. 51.7 N.A. N.A. N.A.
Protein Similarity: 100 97.3 77.8 97 N.A. 97.6 97.4 N.A. N.A. 94.5 77.6 N.A. N.A. 68.1 N.A. N.A. N.A.
P-Site Identity: 100 93.3 20 80 N.A. 86.6 86.6 N.A. N.A. 66.6 6.6 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 93.3 40 86.6 N.A. 93.3 86.6 N.A. N.A. 80 13.3 N.A. N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 0 12 12 12 12 12 0 67 67 12 0 % A
% Cys: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % C
% Asp: 0 23 0 0 12 67 12 0 45 0 12 0 12 0 12 % D
% Glu: 0 0 0 0 0 0 0 0 34 0 12 0 0 0 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 78 12 0 0 0 12 0 0 12 56 0 % G
% His: 23 0 0 12 0 12 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 67 0 0 0 0 0 12 78 0 0 0 0 % K
% Leu: 0 12 12 0 12 0 0 12 0 0 0 0 0 12 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 12 0 0 0 % N
% Pro: 78 0 0 0 0 0 0 0 0 67 0 0 0 12 12 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 0 0 12 0 % R
% Ser: 0 67 0 0 0 0 0 45 12 0 0 12 0 0 12 % S
% Thr: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 12 % T
% Val: 0 0 0 0 0 0 45 0 0 0 0 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 78 0 0 0 12 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _