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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MXD4
All Species:
15.76
Human Site:
S185
Identified Species:
38.52
UniProt:
Q14582
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14582
NP_006445.1
209
23528
S185
S
D
A
D
D
H
Y
S
L
Q
S
G
T
G
G
Chimpanzee
Pan troglodytes
XP_517071
209
23643
S185
S
D
A
D
D
H
Y
S
L
Q
S
G
T
G
G
Rhesus Macaque
Macaca mulatta
XP_001118504
455
49732
S431
S
D
A
D
D
H
Y
S
L
Q
S
G
S
G
G
Dog
Lupus familis
XP_545921
209
23619
S185
S
D
V
D
D
H
Y
S
L
Q
S
G
G
C
S
Cat
Felis silvestris
Mouse
Mus musculus
Q60948
209
23572
S185
S
D
A
D
D
H
Y
S
L
Q
S
S
G
C
S
Rat
Rattus norvegicus
O09015
228
26003
H205
S
I
S
D
I
D
D
H
S
S
L
Q
S
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512779
249
28127
H226
S
I
S
D
I
D
D
H
S
S
L
Q
S
I
G
Chicken
Gallus gallus
NP_001006460
205
23539
H182
S
A
S
D
A
E
D
H
Y
S
L
Q
S
G
S
Frog
Xenopus laevis
Q0VH34
221
25215
E189
S
S
V
S
D
L
D
E
R
E
S
M
Q
S
I
Zebra Danio
Brachydanio rerio
Q7SX95
200
23000
L176
V
E
S
M
V
W
T
L
E
A
D
A
L
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88
45.2
91.8
N.A.
90.4
50.8
N.A.
43.7
81.8
47
48.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.9
45.4
95.6
N.A.
93.3
65.3
N.A.
59
90.4
65.6
67.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
73.3
20
N.A.
20
20
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
73.3
33.3
N.A.
33.3
33.3
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
40
0
10
0
0
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% C
% Asp:
0
50
0
80
60
20
40
0
0
0
10
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
0
10
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
40
20
50
50
% G
% His:
0
0
0
0
0
50
0
30
0
0
0
0
0
0
0
% H
% Ile:
0
20
0
0
20
0
0
0
0
0
0
0
0
20
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
10
50
0
30
0
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
30
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
90
10
40
10
0
0
0
50
20
30
60
10
40
10
40
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
20
0
0
% T
% Val:
10
0
20
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
50
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _