KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NBR1
All Species:
23.94
Human Site:
S486
Identified Species:
52.67
UniProt:
Q14596
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14596
NP_114068.1
966
107432
S486
D
P
F
P
S
E
E
S
P
D
N
I
E
K
G
Chimpanzee
Pan troglodytes
XP_001155284
964
107188
S486
D
P
F
P
S
E
E
S
P
D
N
I
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001097043
1061
117901
S583
D
P
F
P
S
E
E
S
P
D
N
I
E
K
G
Dog
Lupus familis
XP_537628
1032
114204
S537
D
P
F
P
S
T
E
S
P
E
N
I
E
K
G
Cat
Felis silvestris
Mouse
Mus musculus
P97432
988
109939
S487
D
P
F
P
S
S
E
S
P
D
N
V
E
G
D
Rat
Rattus norvegicus
Q501R9
983
109810
S488
D
P
F
P
S
S
E
S
P
V
N
L
E
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518121
1121
119530
Y595
A
P
G
L
E
G
T
Y
T
S
H
W
R
L
A
Chicken
Gallus gallus
XP_418128
956
107389
S468
D
P
S
P
A
T
D
S
L
E
S
N
W
K
D
Frog
Xenopus laevis
NP_001079967
969
107481
I485
D
T
I
A
C
N
D
I
L
E
H
T
V
K
G
Zebra Danio
Brachydanio rerio
XP_001922991
992
107834
I477
D
P
H
A
P
T
A
I
C
A
D
G
L
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791508
1109
122740
P549
D
K
A
E
V
L
E
P
R
C
E
S
K
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
87.7
81.4
N.A.
82.7
82.3
N.A.
38.2
61.1
45.4
44
N.A.
N.A.
N.A.
N.A.
26.6
Protein Similarity:
100
99.6
89
85.1
N.A.
87.7
88
N.A.
49.6
74
58.8
59
N.A.
N.A.
N.A.
N.A.
44.4
P-Site Identity:
100
100
100
86.6
N.A.
73.3
66.6
N.A.
6.6
33.3
20
13.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
13.3
60
40
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
10
0
10
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
91
0
0
0
0
0
19
0
0
37
10
0
0
0
28
% D
% Glu:
0
0
0
10
10
28
64
0
0
28
10
0
55
0
0
% E
% Phe:
0
0
55
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
0
0
0
0
0
10
0
10
46
% G
% His:
0
0
10
0
0
0
0
0
0
0
19
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
19
0
0
0
37
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
10
64
0
% K
% Leu:
0
0
0
10
0
10
0
0
19
0
0
10
10
19
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
55
10
0
0
0
% N
% Pro:
0
82
0
64
10
0
0
10
55
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% R
% Ser:
0
0
10
0
55
19
0
64
0
10
10
10
0
0
0
% S
% Thr:
0
10
0
0
0
28
10
0
10
0
0
10
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
0
10
0
10
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _