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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IHH
All Species:
18.18
Human Site:
S374
Identified Species:
36.36
UniProt:
Q14623
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14623
NP_002172.2
411
45251
S374
F
H
S
L
A
W
G
S
W
T
P
G
E
G
V
Chimpanzee
Pan troglodytes
XP_526034
411
45281
S374
F
H
S
L
A
W
G
S
W
T
P
G
E
G
V
Rhesus Macaque
Macaca mulatta
XP_001092385
526
57459
S489
F
H
S
L
A
W
G
S
W
T
P
G
E
G
V
Dog
Lupus familis
XP_545653
373
40806
S336
F
H
S
L
A
W
G
S
W
T
P
G
E
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P97812
411
45466
S374
F
P
S
L
A
W
G
S
W
T
P
S
E
G
V
Rat
Rattus norvegicus
Q63673
437
47612
G400
Q
S
V
A
E
A
R
G
A
G
P
P
A
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514443
688
74066
S650
P
G
P
P
A
C
C
S
G
L
G
P
A
S
P
Chicken
Gallus gallus
Q98938
408
44811
P371
Y
H
S
L
L
G
G
P
G
V
Q
G
D
G
V
Frog
Xenopus laevis
Q91612
409
45573
Q372
L
G
I
I
A
G
T
Q
P
S
Q
Q
M
G
I
Zebra Danio
Brachydanio rerio
Q90419
416
46558
V380
F
P
A
R
E
S
N
V
N
F
Q
E
D
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02936
471
52132
L427
L
S
T
L
E
A
W
L
P
A
K
E
Q
L
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001012720
411
46240
M372
Y
S
Y
I
R
H
N
M
L
G
I
V
D
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
77.7
77.3
N.A.
95.1
59.2
N.A.
42.5
78
69.8
58.4
N.A.
41.4
N.A.
N.A.
48.6
Protein Similarity:
100
99.2
78.1
79.8
N.A.
97.5
68.4
N.A.
47
82.9
79
71.6
N.A.
55.6
N.A.
N.A.
65.2
P-Site Identity:
100
100
100
100
N.A.
86.6
13.3
N.A.
13.3
46.6
13.3
13.3
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
20
N.A.
13.3
60
33.3
33.3
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
59
17
0
0
9
9
0
0
17
0
0
% A
% Cys:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% D
% Glu:
0
0
0
0
25
0
0
0
0
0
0
17
42
0
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
17
50
9
17
17
9
42
0
75
0
% G
% His:
0
42
0
0
0
9
0
0
0
0
0
0
0
0
9
% H
% Ile:
0
0
9
17
0
0
0
0
0
0
9
0
0
0
25
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
17
0
0
59
9
0
0
9
9
9
0
0
0
9
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
17
0
9
0
0
0
0
0
9
% N
% Pro:
9
17
9
9
0
0
0
9
17
0
50
17
0
0
9
% P
% Gln:
9
0
0
0
0
0
0
9
0
0
25
9
9
0
0
% Q
% Arg:
0
0
0
9
9
0
9
0
0
0
0
0
0
0
0
% R
% Ser:
0
25
50
0
0
9
0
50
0
9
0
9
0
9
0
% S
% Thr:
0
0
9
0
0
0
9
0
0
42
0
0
0
9
0
% T
% Val:
0
0
9
0
0
0
0
9
0
9
0
9
0
0
50
% V
% Trp:
0
0
0
0
0
42
9
0
42
0
0
0
0
0
0
% W
% Tyr:
17
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _