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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IHH
All Species:
13.64
Human Site:
S407
Identified Species:
27.27
UniProt:
Q14623
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14623
NP_002172.2
411
45251
S407
S
F
H
P
L
G
M
S
G
A
G
S
_
_
_
Chimpanzee
Pan troglodytes
XP_526034
411
45281
S407
S
F
H
P
L
G
M
S
G
A
G
S
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001092385
526
57459
S522
S
F
H
P
L
G
M
S
G
A
G
S
_
_
_
Dog
Lupus familis
XP_545653
373
40806
A369
S
F
H
S
L
G
M
A
G
P
G
S
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
P97812
411
45466
S407
T
F
H
P
L
G
M
S
G
A
G
S
_
_
_
Rat
Rattus norvegicus
Q63673
437
47612
A433
T
L
H
P
L
G
M
A
V
K
S
S
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514443
688
74066
N683
E
R
D
P
R
R
E
N
R
D
A
R
H
_
_
Chicken
Gallus gallus
Q98938
408
44811
P404
S
F
H
P
L
G
A
P
R
A
E
S
_
_
_
Frog
Xenopus laevis
Q91612
409
45573
V405
E
F
H
P
L
G
I
V
Q
L
E
S
_
_
_
Zebra Danio
Brachydanio rerio
Q90419
416
46558
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02936
471
52132
K460
A
N
A
L
Y
K
V
K
D
Y
V
L
P
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001012720
411
46240
L405
K
Y
V
M
S
D
R
L
F
L
G
F
D
V
_
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
77.7
77.3
N.A.
95.1
59.2
N.A.
42.5
78
69.8
58.4
N.A.
41.4
N.A.
N.A.
48.6
Protein Similarity:
100
99.2
78.1
79.8
N.A.
97.5
68.4
N.A.
47
82.9
79
71.6
N.A.
55.6
N.A.
N.A.
65.2
P-Site Identity:
100
100
100
75
N.A.
91.6
50
N.A.
7.6
66.6
50
0
N.A.
0
N.A.
N.A.
7.1
P-Site Similarity:
100
100
100
83.3
N.A.
100
66.6
N.A.
15.3
66.6
58.3
0
N.A.
13.3
N.A.
N.A.
14.2
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
9
17
0
42
9
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
9
9
0
0
9
0
0
% D
% Glu:
17
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% E
% Phe:
0
59
0
0
0
0
0
0
9
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
0
67
0
0
42
0
50
0
0
0
0
% G
% His:
0
0
67
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
9
0
9
0
9
0
0
0
0
0
% K
% Leu:
0
9
0
9
67
0
0
9
0
17
0
9
0
0
0
% L
% Met:
0
0
0
9
0
0
50
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
67
0
0
0
9
0
9
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% Q
% Arg:
0
9
0
0
9
9
9
0
17
0
0
9
0
0
0
% R
% Ser:
42
0
0
9
9
0
0
34
0
0
9
67
0
0
9
% S
% Thr:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
9
9
9
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
67
75
84
% _