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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IHH
All Species:
22.73
Human Site:
S53
Identified Species:
45.45
UniProt:
Q14623
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14623
NP_002172.2
411
45251
S53
P
L
A
Y
K
Q
F
S
P
N
V
P
E
K
T
Chimpanzee
Pan troglodytes
XP_526034
411
45281
S53
P
L
A
Y
K
Q
F
S
P
N
V
P
E
K
T
Rhesus Macaque
Macaca mulatta
XP_001092385
526
57459
S168
P
L
A
Y
K
Q
F
S
P
N
V
P
E
K
T
Dog
Lupus familis
XP_545653
373
40806
F34
E
Q
S
T
L
P
G
F
P
T
P
A
D
A
L
Cat
Felis silvestris
Mouse
Mus musculus
P97812
411
45466
S53
P
L
A
Y
K
Q
F
S
P
N
V
P
E
K
T
Rat
Rattus norvegicus
Q63673
437
47612
I49
P
L
A
Y
K
Q
F
I
P
N
V
A
E
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514443
688
74066
L313
H
L
P
P
L
R
L
L
P
L
A
W
T
R
I
Chicken
Gallus gallus
Q98938
408
44811
S49
P
L
A
Y
K
Q
F
S
P
N
V
P
E
K
T
Frog
Xenopus laevis
Q91612
409
45573
S48
P
L
S
Y
K
Q
F
S
P
N
V
P
E
K
T
Zebra Danio
Brachydanio rerio
Q90419
416
46558
I51
P
L
A
Y
K
Q
F
I
P
N
V
A
E
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02936
471
52132
I108
P
L
V
L
K
Q
T
I
P
N
L
S
E
Y
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001012720
411
46240
V51
P
L
Q
Y
K
Q
R
V
P
N
I
S
E
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
77.7
77.3
N.A.
95.1
59.2
N.A.
42.5
78
69.8
58.4
N.A.
41.4
N.A.
N.A.
48.6
Protein Similarity:
100
99.2
78.1
79.8
N.A.
97.5
68.4
N.A.
47
82.9
79
71.6
N.A.
55.6
N.A.
N.A.
65.2
P-Site Identity:
100
100
100
6.6
N.A.
100
86.6
N.A.
13.3
100
93.3
86.6
N.A.
53.3
N.A.
N.A.
60
P-Site Similarity:
100
100
100
20
N.A.
100
86.6
N.A.
26.6
100
100
86.6
N.A.
60
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
59
0
0
0
0
0
0
0
9
25
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
84
0
0
% E
% Phe:
0
0
0
0
0
0
67
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
25
0
0
9
0
0
0
9
% I
% Lys:
0
0
0
0
84
0
0
0
0
0
0
0
0
67
0
% K
% Leu:
0
92
0
9
17
0
9
9
0
9
9
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
84
0
0
0
0
0
% N
% Pro:
84
0
9
9
0
9
0
0
100
0
9
50
0
0
0
% P
% Gln:
0
9
9
0
0
84
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
9
0
0
0
0
0
0
9
0
% R
% Ser:
0
0
17
0
0
0
0
50
0
0
0
17
0
0
0
% S
% Thr:
0
0
0
9
0
0
9
0
0
9
0
0
9
0
84
% T
% Val:
0
0
9
0
0
0
0
9
0
0
67
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
75
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _