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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL11RA All Species: 5.15
Human Site: S401 Identified Species: 14.17
UniProt: Q14626 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14626 NP_001136256.1 422 45222 S401 R R G G K D G S P K P G F L A
Chimpanzee Pan troglodytes XP_528589 566 61567 S545 R Q G G K D G S P K T G F L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538710 330 35305 L315 R P Q K P G F L A P V I P V D
Cat Felis silvestris
Mouse Mus musculus Q64385 432 46636 P403 R R S G K D G P Q K P G L L A
Rat Rattus norvegicus Q99MF4 431 46766 P402 R R S G K D G P Q K P G F L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518303 676 74265 A651 R R A P L E Q A A V V V S V G
Chicken Gallus gallus P51641 362 40289 C347 G S G A V A V C W T A G L V L
Frog Xenopus laevis NP_001080560 396 44902 S381 I G S T V R L S W L P A L L L
Zebra Danio Brachydanio rerio NP_001106971 402 44912 N385 V R Q R K Q D N V K K Q E L T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.5 N.A. 67.3 N.A. 82.1 80.5 N.A. 35.6 28.2 28.6 30.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 74 N.A. 69.9 N.A. 86.3 85.3 N.A. 42.1 43.1 45.2 46.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 N.A. 6.6 N.A. 73.3 80 N.A. 13.3 13.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 N.A. 13.3 N.A. 73.3 80 N.A. 33.3 20 20 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 12 0 12 0 12 23 0 12 12 0 0 45 % A
% Cys: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 45 12 0 0 0 0 0 0 0 12 % D
% Glu: 0 0 0 0 0 12 0 0 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 12 0 0 0 0 0 34 0 0 % F
% Gly: 12 12 34 45 0 12 45 0 0 0 0 56 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % I
% Lys: 0 0 0 12 56 0 0 0 0 56 12 0 0 0 0 % K
% Leu: 0 0 0 0 12 0 12 12 0 12 0 0 34 67 23 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 12 12 0 0 23 23 12 45 0 12 0 0 % P
% Gln: 0 12 23 0 0 12 12 0 23 0 0 12 0 0 0 % Q
% Arg: 67 56 0 12 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 12 34 0 0 0 0 34 0 0 0 0 12 0 0 % S
% Thr: 0 0 0 12 0 0 0 0 0 12 12 0 0 0 12 % T
% Val: 12 0 0 0 23 0 12 0 12 12 23 12 0 34 0 % V
% Trp: 0 0 0 0 0 0 0 0 23 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _