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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5A All Species: 29.39
Human Site: S330 Identified Species: 58.79
UniProt: Q14642 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14642 NP_005530.3 412 47820 S330 F P P S Y P Y S E D A R Q G E
Chimpanzee Pan troglodytes XP_001155993 414 48224 S330 F P P S Y P Y S E D A R Q G E
Rhesus Macaque Macaca mulatta XP_001113817 361 41727 L311 P S A K E L V L R S E S E E K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus NP_898967 422 48794 S330 F P P S Y P Y S E D S S Q G E
Rat Rattus norvegicus NP_001102393 412 47604 S330 F P P S Y P Y S E D S S Q G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421831 502 57686 S420 F P P S Y P Y S E D S S Q G K
Frog Xenopus laevis NP_001087708 412 47382 S330 F P P S Y P Y S E D S S Q G K
Zebra Danio Brachydanio rerio NP_001032658 396 45953 S325 F P P S Y P Y S E D Y T K P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001138109 786 88564 E331 F V P S Y P F E E D P E M P T
Honey Bee Apis mellifera NP_001011585 388 45250 E323 F V P S Y P F E E D I N E G S
Nematode Worm Caenorhab. elegans Q17848 409 47583 S350 F P P T Y P W S E D P E N S E
Sea Urchin Strong. purpuratus XP_782162 345 40063 S295 D R V F M S H S A K A L I S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.8 66.5 N.A. N.A. 92.4 97 N.A. N.A. 74.3 82.7 52.6 N.A. 24.5 49.2 29.3 39
Protein Similarity: 100 96.8 73.7 N.A. N.A. 94.5 98.7 N.A. N.A. 78.8 91.2 69.9 N.A. 35.3 66 49.7 55.3
P-Site Identity: 100 100 0 N.A. N.A. 86.6 86.6 N.A. N.A. 80 80 66.6 N.A. 46.6 53.3 60 13.3
P-Site Similarity: 100 100 13.3 N.A. N.A. 93.3 93.3 N.A. N.A. 93.3 93.3 73.3 N.A. 53.3 66.6 73.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 0 0 9 0 25 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 0 84 0 0 0 0 9 % D
% Glu: 0 0 0 0 9 0 0 17 84 0 9 17 17 9 42 % E
% Phe: 84 0 0 9 0 0 17 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % I
% Lys: 0 0 0 9 0 0 0 0 0 9 0 0 9 0 25 % K
% Leu: 0 0 0 0 0 9 0 9 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % N
% Pro: 9 67 84 0 0 84 0 0 0 0 17 0 0 17 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 9 0 0 17 0 0 0 % R
% Ser: 0 9 0 75 0 9 0 75 0 9 34 42 0 17 9 % S
% Thr: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 17 % T
% Val: 0 17 9 0 0 0 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 84 0 59 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _