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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPR1
All Species:
17.88
Human Site:
Y1181
Identified Species:
43.7
UniProt:
Q14643
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14643
NP_001093422.1
2758
313945
Y1181
K
H
E
S
T
S
S
Y
N
Y
R
V
V
K
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102937
2700
308048
K1167
P
V
Q
D
G
T
K
K
P
Q
I
D
S
N
K
Dog
Lupus familis
XP_851008
2757
314037
Y1180
K
H
E
S
T
S
S
Y
N
Y
R
V
V
K
E
Cat
Felis silvestris
Mouse
Mus musculus
P11881
2749
313179
Y1171
K
H
E
S
T
S
S
Y
N
Y
R
V
V
K
E
Rat
Rattus norvegicus
P29994
2750
313246
Y1171
K
H
E
S
T
S
S
Y
N
Y
R
V
V
K
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001167530
2712
309042
Y1171
K
P
E
S
T
S
S
Y
N
Y
R
V
V
K
E
Frog
Xenopus laevis
NP_001084015
2693
306654
R1152
S
T
S
S
Y
N
Y
R
V
V
K
E
I
L
L
Zebra Danio
Brachydanio rerio
XP_001921194
2691
306311
P1169
K
L
C
V
Q
E
G
P
S
G
K
K
S
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29993
2838
319089
V1276
Q
R
N
E
Y
R
K
V
K
E
I
L
I
R
M
Honey Bee
Apis mellifera
XP_392236
2749
311321
I1180
Q
A
E
E
Y
K
K
I
Q
Q
I
L
I
R
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
68.8
98.6
N.A.
98.2
98.2
N.A.
N.A.
93.6
87.8
85.4
N.A.
58.5
62.5
N.A.
N.A.
Protein Similarity:
100
N.A.
80.8
99.2
N.A.
99
98.9
N.A.
N.A.
96.1
92.3
91.3
N.A.
72.1
76.7
N.A.
N.A.
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
N.A.
93.3
6.6
13.3
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
N.A.
93.3
26.6
33.3
N.A.
26.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
60
20
0
10
0
0
0
10
0
10
0
0
50
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
40
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
30
0
30
0
0
% I
% Lys:
60
0
0
0
0
10
30
10
10
0
20
10
0
60
20
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
0
20
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% M
% Asn:
0
0
10
0
0
10
0
0
50
0
0
0
0
10
0
% N
% Pro:
10
10
0
0
0
0
0
10
10
0
0
0
0
0
0
% P
% Gln:
20
0
10
0
10
0
0
0
10
20
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
10
0
0
50
0
0
20
0
% R
% Ser:
10
0
10
60
0
50
50
0
10
0
0
0
20
0
0
% S
% Thr:
0
10
0
0
50
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
10
0
0
0
10
10
10
0
50
50
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
30
0
10
50
0
50
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _