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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLS1
All Species:
17.88
Human Site:
S509
Identified Species:
35.76
UniProt:
Q14651
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14651
NP_001138791.1
629
70253
S509
R
Y
T
L
N
V
L
S
D
L
G
E
G
E
K
Chimpanzee
Pan troglodytes
XP_001157345
627
70271
E508
R
Y
T
L
N
I
L
E
E
I
G
G
G
Q
K
Rhesus Macaque
Macaca mulatta
XP_001112046
629
70237
S509
R
Y
T
L
N
V
L
S
D
L
G
E
G
E
K
Dog
Lupus familis
XP_542817
767
86003
S647
R
Y
T
L
N
V
L
S
D
L
G
E
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0K9
630
70389
S510
R
Y
T
L
K
V
L
S
D
L
G
E
G
E
K
Rat
Rattus norvegicus
Q63598
630
70661
E511
R
Y
T
L
N
V
M
E
D
L
G
E
G
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514284
674
75344
E555
R
Y
T
L
Q
I
L
E
D
I
G
G
G
Q
K
Chicken
Gallus gallus
P19179
630
70921
S510
R
Y
T
L
N
V
L
S
D
L
G
E
G
E
K
Frog
Xenopus laevis
NP_001083581
629
70942
E509
R
Y
T
L
N
V
L
E
D
L
G
E
G
Q
K
Zebra Danio
Brachydanio rerio
Q6P698
624
69882
E506
R
Y
T
L
N
I
L
E
D
L
G
D
G
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G188
687
76910
K503
F
H
M
L
Q
L
L
K
S
L
R
S
R
T
L
Baker's Yeast
Sacchar. cerevisiae
P32599
642
71754
K526
R
N
I
S
I
T
M
K
T
L
S
S
S
G
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
99.3
77
N.A.
94.2
74.9
N.A.
69.1
86.3
76.4
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.1
99.8
79.6
N.A.
97.4
87.4
N.A.
81.3
94.2
87.9
85.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
100
100
N.A.
93.3
80
N.A.
60
100
86.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
93.3
93.3
N.A.
80
100
93.3
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
39.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.6
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
75
0
0
9
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
42
9
0
0
59
0
42
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
84
17
84
9
0
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
25
0
0
0
17
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
17
0
0
0
0
0
0
84
% K
% Leu:
0
0
0
92
0
9
84
0
0
84
0
0
0
0
9
% L
% Met:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
67
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
0
42
0
% Q
% Arg:
92
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% R
% Ser:
0
0
0
9
0
0
0
42
9
0
9
17
9
0
0
% S
% Thr:
0
0
84
0
0
9
0
0
9
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
59
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _