KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLS1
All Species:
35.15
Human Site:
Y375
Identified Species:
70.3
UniProt:
Q14651
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14651
NP_001138791.1
629
70253
Y375
V
A
N
L
F
N
T
Y
P
C
L
H
K
P
N
Chimpanzee
Pan troglodytes
XP_001157345
627
70271
Y374
I
A
N
L
F
N
R
Y
P
A
L
H
K
P
E
Rhesus Macaque
Macaca mulatta
XP_001112046
629
70237
Y375
V
A
N
L
F
N
T
Y
P
C
L
H
K
P
N
Dog
Lupus familis
XP_542817
767
86003
Y514
V
A
N
L
F
N
T
Y
P
C
L
H
K
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0K9
630
70389
Y376
V
A
N
L
F
N
T
Y
P
C
L
H
K
P
D
Rat
Rattus norvegicus
Q63598
630
70661
Y377
V
A
N
L
F
N
K
Y
P
A
L
T
K
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514284
674
75344
Y421
I
A
N
L
F
N
R
Y
P
A
L
H
K
P
E
Chicken
Gallus gallus
P19179
630
70921
Y376
V
A
N
L
F
N
T
Y
P
A
L
H
K
P
D
Frog
Xenopus laevis
NP_001083581
629
70942
Y375
V
A
N
L
F
N
K
Y
P
A
L
T
K
P
V
Zebra Danio
Brachydanio rerio
Q6P698
624
69882
Y372
V
A
N
L
F
N
K
Y
P
A
L
K
K
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7G188
687
76910
R370
V
A
Q
I
F
H
E
R
N
G
L
N
K
D
G
Baker's Yeast
Sacchar. cerevisiae
P32599
642
71754
H389
V
A
H
L
F
N
T
H
P
G
L
E
P
I
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.4
99.3
77
N.A.
94.2
74.9
N.A.
69.1
86.3
76.4
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.1
99.8
79.6
N.A.
97.4
87.4
N.A.
81.3
94.2
87.9
85.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
100
93.3
N.A.
93.3
73.3
N.A.
73.3
86.6
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
100
N.A.
100
73.3
N.A.
80
93.3
73.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.2
39.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.6
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
100
0
0
0
0
0
0
0
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
34
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
25
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
34
% E
% Phe:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
9
% G
% His:
0
0
9
0
0
9
0
9
0
0
0
59
0
0
0
% H
% Ile:
17
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
25
0
0
0
0
9
92
0
0
% K
% Leu:
0
0
0
92
0
0
0
0
0
0
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
84
0
0
92
0
0
9
0
0
9
0
0
17
% N
% Pro:
0
0
0
0
0
0
0
0
92
0
0
0
9
84
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
50
0
0
0
0
17
0
0
0
% T
% Val:
84
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
84
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _