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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNJ11 All Species: 30.3
Human Site: S331 Identified Species: 74.07
UniProt: Q14654 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14654 NP_000516 390 43541 S331 G R Y S V D Y S K F G N T I K
Chimpanzee Pan troglodytes XP_521849 390 43540 S331 G R Y S V D Y S K F G N T I K
Rhesus Macaque Macaca mulatta XP_001089155 390 43552 S331 G R Y S V D Y S K F G N T I K
Dog Lupus familis XP_542519 390 43410 S331 G R Y S V D Y S K F G N T I K
Cat Felis silvestris
Mouse Mus musculus Q61743 390 43543 S331 G R Y S V D Y S K F G N T I K
Rat Rattus norvegicus P70673 390 43589 S331 G R Y S V D Y S K F G N T V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509905 401 44343 S343 G R Y S V D Y S K F G N T V K
Chicken Gallus gallus Q90854 492 55398 S335 G F F K V D Y S Q F H A T F E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001034916 381 42766 G323 P T V S E E D G M Y A V D Y S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52192 505 57401 N417 H E H K L E D N R S S D S T P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.9 97.4 N.A. 96.4 96.1 N.A. 87 37.2 N.A. 70.2 N.A. N.A. N.A. 33 N.A.
Protein Similarity: 100 99.7 99.4 98.4 N.A. 97.6 97.6 N.A. 92.7 55.6 N.A. 81.5 N.A. N.A. N.A. 51 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. 93.3 46.6 N.A. 6.6 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 66.6 N.A. 20 N.A. N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 80 20 0 0 0 0 10 10 0 0 % D
% Glu: 0 10 0 0 10 20 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 10 10 0 0 0 0 0 0 80 0 0 0 10 0 % F
% Gly: 80 0 0 0 0 0 0 10 0 0 70 0 0 0 0 % G
% His: 10 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % I
% Lys: 0 0 0 20 0 0 0 0 70 0 0 0 0 0 70 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 70 0 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 70 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 80 0 0 0 80 0 10 10 0 10 0 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 80 10 0 % T
% Val: 0 0 10 0 80 0 0 0 0 0 0 10 0 20 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 70 0 0 0 80 0 0 10 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _