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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM187
All Species:
12.73
Human Site:
Y185
Identified Species:
56
UniProt:
Q14656
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14656
NP_003483.1
261
29148
Y185
A
L
R
T
H
R
H
Y
G
S
T
T
S
A
T
Chimpanzee
Pan troglodytes
XP_521331
261
29179
Y185
A
L
R
T
H
R
H
Y
G
S
T
T
S
A
T
Rhesus Macaque
Macaca mulatta
XP_001089448
261
29131
Y185
A
L
R
T
H
R
H
Y
G
S
T
T
S
A
T
Dog
Lupus familis
XP_855359
266
29824
Y191
A
L
R
T
H
R
R
Y
G
S
A
T
S
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341471
256
28954
H185
G
V
R
A
Q
L
K
H
G
D
S
A
S
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001202883
89
9898
C24
V
S
S
S
W
N
L
C
T
K
Y
T
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
94.2
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
51.3
N.A.
N.A.
N.A.
N.A.
20.3
Protein Similarity:
100
99.6
96.5
80.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
62.8
N.A.
N.A.
N.A.
N.A.
25.2
P-Site Identity:
100
100
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
0
17
0
0
0
0
0
0
17
17
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
0
0
0
0
0
0
0
84
0
0
0
0
17
17
% G
% His:
0
0
0
0
67
0
50
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
17
0
0
17
0
0
0
0
0
% K
% Leu:
0
67
0
0
0
17
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
17
17
0
% P
% Gln:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
84
0
0
67
17
0
0
0
0
0
0
0
17
% R
% Ser:
0
17
17
17
0
0
0
0
0
67
17
0
84
0
0
% S
% Thr:
0
0
0
67
0
0
0
0
17
0
50
84
0
0
67
% T
% Val:
17
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _