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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LAGE3
All Species:
3.33
Human Site:
S22
Identified Species:
14.67
UniProt:
Q14657
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14657
NP_006005.2
143
14804
S22
G
D
G
R
G
G
H
S
C
R
G
G
V
D
T
Chimpanzee
Pan troglodytes
XP_521343
84
9273
Rhesus Macaque
Macaca mulatta
XP_001102130
143
14784
S22
G
D
S
Q
G
D
H
S
C
P
G
G
A
D
T
Dog
Lupus familis
XP_855388
236
26024
L74
L
N
L
V
V
K
P
L
E
K
V
L
L
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR70
148
15806
C22
A
D
G
Q
T
S
R
C
C
P
G
N
A
G
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120975
89
10095
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.7
83.2
35.1
N.A.
54
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
24.4
N.A.
N.A.
Protein Similarity:
100
58.7
87.4
42.7
N.A.
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
37
N.A.
N.A.
P-Site Identity:
100
0
66.6
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
0
73.3
26.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
17
50
0
0
0
0
0
0
% C
% Asp:
0
50
0
0
0
17
0
0
0
0
0
0
0
34
0
% D
% Glu:
0
0
0
0
0
0
0
0
17
0
0
0
0
17
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
34
0
34
17
0
0
0
0
50
34
0
17
0
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
17
0
0
0
17
0
0
0
0
0
% K
% Leu:
17
0
17
0
0
0
0
17
0
0
0
17
17
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
0
0
0
0
0
0
0
0
17
0
0
0
% N
% Pro:
0
0
0
0
0
0
17
0
0
34
0
0
0
0
0
% P
% Gln:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
17
0
0
17
0
0
17
0
0
0
0
0
% R
% Ser:
0
0
17
0
0
17
0
34
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
50
% T
% Val:
0
0
0
17
17
0
0
0
0
0
17
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _