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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LAGE3 All Species: 7.88
Human Site: T64 Identified Species: 34.67
UniProt: Q14657 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14657 NP_006005.2 143 14804 T64 R M R P H I F T L S V P F P T
Chimpanzee Pan troglodytes XP_521343 84 9273 T12 T L S V P F P T P L E A E I A
Rhesus Macaque Macaca mulatta XP_001102130 143 14784 T64 G M R P H V F T L S V P F P T
Dog Lupus familis XP_855388 236 26024 A157 T E A M E K G A L C V P F P S
Cat Felis silvestris
Mouse Mus musculus Q9CR70 148 15806 S69 G T R H H R F S L F V P F P T
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120975 89 10095 E17 I P F P S S R E A E I V Y Q V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.7 83.2 35.1 N.A. 54 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 24.4 N.A. N.A.
Protein Similarity: 100 58.7 87.4 42.7 N.A. 63.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 37 N.A. N.A.
P-Site Identity: 100 6.6 86.6 33.3 N.A. 60 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 13.3 93.3 40 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 0 17 17 0 0 17 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 17 0 0 17 0 0 17 0 17 17 0 17 0 0 % E
% Phe: 0 0 17 0 0 17 50 0 0 17 0 0 67 0 0 % F
% Gly: 34 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 17 50 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 17 0 0 0 0 17 0 0 0 0 17 0 0 17 0 % I
% Lys: 0 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 17 0 0 0 0 0 0 67 17 0 0 0 0 0 % L
% Met: 0 34 0 17 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 0 50 17 0 17 0 17 0 0 67 0 67 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % Q
% Arg: 17 0 50 0 0 17 17 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 17 0 17 17 0 17 0 34 0 0 0 0 17 % S
% Thr: 34 17 0 0 0 0 0 50 0 0 0 0 0 0 50 % T
% Val: 0 0 0 17 0 17 0 0 0 0 67 17 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _