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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0100 All Species: 23.64
Human Site: S1457 Identified Species: 52
UniProt: Q14667 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14667 NP_055495.2 2235 253700 S1457 H L V D L R I S W T T T N R D
Chimpanzee Pan troglodytes XP_523588 1990 224800 S1309 V V F T E E E S G M S D Q L C
Rhesus Macaque Macaca mulatta XP_001108491 2235 253532 S1457 H L V D L R I S W T T T N R D
Dog Lupus familis XP_537745 2230 253398 S1452 H L V D L R A S W T T T N R D
Cat Felis silvestris
Mouse Mus musculus Q5SYL3 2234 254451 S1457 Y L V D L R I S W T T T N R D
Rat Rattus norvegicus XP_220636 2234 254217 S1457 Y L V D L R I S W T T T N R D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415819 2334 263842 S1469 H L V D L R A S W T T T N R D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647789 2300 262719 K1503 Q S T T P T H K L V V Y D L K
Honey Bee Apis mellifera XP_624880 2023 228811 S1342 K G F H R E S S S T P H K N R
Nematode Worm Caenorhab. elegans NP_493625 2132 246639 L1398 A Q N R D A C L T I A D G V H
Sea Urchin Strong. purpuratus XP_001179093 1445 161489 A764 R F F K K V M A F F F P G R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.6 99 94.8 N.A. 94.5 94.1 N.A. N.A. 77.2 N.A. N.A. N.A. 31 33.7 26.8 22.8
Protein Similarity: 100 88.8 99.5 96.4 N.A. 96.8 96.5 N.A. N.A. 84.6 N.A. N.A. N.A. 50 52.3 45.8 38.8
P-Site Identity: 100 6.6 100 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 N.A. N.A. N.A. 0 13.3 0 6.6
P-Site Similarity: 100 20 100 93.3 N.A. 100 100 N.A. N.A. 93.3 N.A. N.A. N.A. 6.6 13.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 19 10 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 55 10 0 0 0 0 0 0 19 10 0 55 % D
% Glu: 0 0 0 0 10 19 10 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 28 0 0 0 0 0 10 10 10 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 10 0 0 0 19 0 0 % G
% His: 37 0 0 10 0 0 10 0 0 0 0 10 0 0 10 % H
% Ile: 0 0 0 0 0 0 37 0 0 10 0 0 0 0 0 % I
% Lys: 10 0 0 10 10 0 0 10 0 0 0 0 10 0 10 % K
% Leu: 0 55 0 0 55 0 0 10 10 0 0 0 0 19 0 % L
% Met: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 55 10 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 10 10 0 0 0 % P
% Gln: 10 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 10 0 0 10 10 55 0 0 0 0 0 0 0 64 10 % R
% Ser: 0 10 0 0 0 0 10 73 10 0 10 0 0 0 10 % S
% Thr: 0 0 10 19 0 10 0 0 10 64 55 55 0 0 0 % T
% Val: 10 10 55 0 0 10 0 0 0 10 10 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 55 0 0 0 0 0 0 % W
% Tyr: 19 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _