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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 38.48
Human Site: S1057 Identified Species: 70.56
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 S1057 W G R L S T Q S N S N N I E P
Chimpanzee Pan troglodytes XP_001138519 1992 220427 S1057 W G R L S T Q S N S N N I E P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 S1057 W G R L S A Q S N S N N I E P
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 S1090 W G R L S A Q S N S N N I E P
Rat Rattus norvegicus NP_001026829 1976 218189 S1090 W G R L S A Q S N S N N I E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 S1064 W G R L S T Q S N S N N I E P
Chicken Gallus gallus XP_422603 1995 220955 S1060 W G R L S T Q S N S N N I E P
Frog Xenopus laevis NP_001084531 2027 224405 S1097 W G R L S T Q S N S N N I E P
Zebra Danio Brachydanio rerio XP_001919036 1688 188921 C841 Q M D S G V E C L E E I S S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 S1734 W G R K S S S S N S A N D K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 S1587 W G R G A S N S P S S A N T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 S987 T E P G T L P S G A G V S S P
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824 S635 E D G N E N I S L S D E E G D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 100 100 100 0 N.A. N.A. 53.3 N.A. 33.3
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 100 100 100 6.6 N.A. N.A. 66.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 24 0 0 0 8 8 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 0 0 0 0 0 8 0 8 0 8 % D
% Glu: 8 8 0 0 8 0 8 0 0 8 8 8 8 62 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 77 8 16 8 0 0 0 8 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 62 0 8 % I
% Lys: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % K
% Leu: 0 0 0 62 0 8 0 0 16 0 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 8 0 70 0 62 70 8 0 0 % N
% Pro: 0 0 8 0 0 0 8 0 8 0 0 0 0 0 70 % P
% Gln: 8 0 0 0 0 0 62 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 77 0 0 0 0 0 0 0 0 0 0 0 8 % R
% Ser: 0 0 0 8 70 16 8 93 0 85 8 0 16 16 0 % S
% Thr: 8 0 0 0 8 39 0 0 0 0 0 0 0 8 8 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 8 0 0 0 % V
% Trp: 77 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _