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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 24.85
Human Site: S129 Identified Species: 45.56
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 S129 L K S A Q S P S T S K A H T R
Chimpanzee Pan troglodytes XP_001138519 1992 220427 S129 L K S A Q S P S T S K A H T R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 S129 L K S A Q S P S T S K A H T R
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 S129 L K S A Q L P S T S K A H T R
Rat Rattus norvegicus NP_001026829 1976 218189 S129 L K S A Q L P S T S K A H T R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 S129 L K S A Q L P S T S K A Y T R
Chicken Gallus gallus XP_422603 1995 220955 K129 T Q L P S T S K A H T R K G G
Frog Xenopus laevis NP_001084531 2027 224405 T165 P S A S L P S T S K A H G R K
Zebra Danio Brachydanio rerio XP_001919036 1688 188921
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 N518 K P F Q E D A N D F F S M I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 T129 H E V C I P V T T L K S K R H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 A133 M D A A A A A A R S A D E D D
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 86.6 0 0 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 93.3 13.3 33.3 0 N.A. N.A. 20 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 54 8 8 16 8 8 0 16 47 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 0 0 8 0 0 8 0 8 8 % D
% Glu: 0 8 0 0 8 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 8 8 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 8 % G
% His: 8 0 0 0 0 0 0 0 0 8 0 8 39 0 8 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 8 % I
% Lys: 8 47 0 0 0 0 0 8 0 8 54 0 16 0 8 % K
% Leu: 47 0 8 0 8 24 0 0 0 8 0 0 0 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 16 47 0 0 0 0 0 0 0 0 % P
% Gln: 0 8 0 8 47 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 8 0 16 47 % R
% Ser: 0 8 47 8 8 24 16 47 8 54 0 16 0 0 0 % S
% Thr: 8 0 0 0 0 8 0 16 54 0 8 0 0 47 0 % T
% Val: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _