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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 26.67
Human Site: S1445 Identified Species: 48.89
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 S1445 W H D G V C P S V S N P L E V
Chimpanzee Pan troglodytes XP_001138519 1992 220427 S1445 W H D G V C P S V S N P L E V
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 S1445 W H D G V C P S V S N P L E V
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 S1478 W H D G V C P S V A N P L E V
Rat Rattus norvegicus NP_001026829 1976 218189 S1429 W H D G V C P S V A N P L E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 S1452 W H D G V C P S V L N P L E V
Chicken Gallus gallus XP_422603 1995 220955 S1448 W H D G V C P S V L N P L E V
Frog Xenopus laevis NP_001084531 2027 224405 R1480 W H D G V C P R I F N P L E A
Zebra Danio Brachydanio rerio XP_001919036 1688 188921 I1177 L L R V L H S I S R Y W F Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 P2114 W L E G T V P P Q R C P L D P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 V1990 W M D G V C P V I Q K E L H K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 E1327 G E L P C D L E K S N S T Y N
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824 A971 E S E A A E E A N E G K K L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 100 N.A. 93.3 93.3 N.A. 93.3 93.3 73.3 0 N.A. N.A. 33.3 N.A. 46.6
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 80 13.3 N.A. N.A. 46.6 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 8 0 16 0 0 0 0 8 % A
% Cys: 0 0 0 0 8 70 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 70 0 0 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 8 16 0 0 8 8 8 0 8 0 8 0 62 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 8 0 0 77 0 0 0 0 0 0 8 0 0 0 0 % G
% His: 0 62 0 0 0 8 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 8 16 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 8 0 8 8 8 0 8 % K
% Leu: 8 16 8 0 8 0 8 0 0 16 0 0 77 8 8 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 70 0 0 0 8 % N
% Pro: 0 0 0 8 0 0 77 8 0 0 0 70 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 8 0 16 0 0 0 0 8 % R
% Ser: 0 8 0 0 0 0 8 54 8 31 0 8 0 0 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 8 70 8 0 8 54 0 0 0 0 0 54 % V
% Trp: 77 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _