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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP12
All Species:
29.39
Human Site:
S206
Identified Species:
53.89
UniProt:
Q14669
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14669
NP_004229.1
1992
220434
S206
A
A
S
T
S
S
S
S
S
A
V
A
S
A
S
Chimpanzee
Pan troglodytes
XP_001138519
1992
220427
S206
A
A
S
T
S
S
S
S
S
A
V
A
S
A
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850221
1992
220390
S206
A
A
S
T
S
S
S
S
S
A
V
A
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
NP_598736
2025
224109
S206
A
A
S
T
S
S
S
S
S
A
I
A
S
A
S
Rat
Rattus norvegicus
NP_001026829
1976
218189
S206
A
A
S
T
S
S
S
S
S
A
V
A
S
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505299
1999
221121
S206
S
S
A
S
T
S
S
S
S
S
A
V
A
S
A
Chicken
Gallus gallus
XP_422603
1995
220955
A206
S
T
S
S
S
S
S
A
V
A
S
A
S
S
T
Frog
Xenopus laevis
NP_001084531
2027
224405
S242
S
S
A
S
T
S
S
S
S
S
A
V
A
S
V
Zebra Danio
Brachydanio rerio
XP_001919036
1688
188921
E73
N
S
S
A
A
R
T
E
E
T
P
Q
G
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392897
2654
295778
Y595
A
H
S
H
S
L
T
Y
V
L
A
R
E
S
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783595
2536
274452
T206
R
F
S
L
S
D
S
T
G
S
V
C
F
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6WWW4
1888
202909
K210
R
A
E
G
E
E
G
K
Q
V
E
A
L
T
Q
Baker's Yeast
Sacchar. cerevisiae
P33202
1483
167824
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
99.1
N.A.
96.6
96
N.A.
95
95.1
88.5
75.8
N.A.
N.A.
40.3
N.A.
48.8
Protein Similarity:
100
99.9
N.A.
99.5
N.A.
97.3
96.6
N.A.
97.5
97.9
93.3
80.5
N.A.
N.A.
54.6
N.A.
61.8
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
100
N.A.
26.6
46.6
26.6
20
N.A.
N.A.
20
N.A.
33.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
86.6
80
80
40
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
47
47
16
8
8
0
0
8
0
47
24
54
16
54
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
8
0
8
8
0
8
0
8
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
8
0
0
0
8
0
8
% G
% His:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
8
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
8
% Q
% Arg:
16
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% R
% Ser:
24
24
70
24
62
62
70
54
54
24
8
0
47
31
47
% S
% Thr:
0
8
0
39
16
0
16
8
0
8
0
0
0
8
8
% T
% Val:
0
0
0
0
0
0
0
0
16
8
39
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _