Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 31.21
Human Site: S252 Identified Species: 57.22
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 S252 S S R E K E Q S K T G G S S K
Chimpanzee Pan troglodytes XP_001138519 1992 220427 S252 S S R E K E Q S K T G G S S K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 S252 S S R E K E Q S K T G G S S K
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 S252 S S R E K E Q S K T G G S S K
Rat Rattus norvegicus NP_001026829 1976 218189 S252 S S R E K E Q S K T G G S S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 S253 S S R E K E Q S K T G S S S K
Chicken Gallus gallus XP_422603 1995 220955 S250 S S R D K E Q S K T G G S S K
Frog Xenopus laevis NP_001084531 2027 224405 T288 S S R E K E Q T K T S G S S K
Zebra Danio Brachydanio rerio XP_001919036 1688 188921 H115 E A R G L P P H L F G P F G P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 K664 V C R D V E E K R R R Q T I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 K336 K A K G T V S K T A I Q K T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 P252 L L N H E S N P D I M L L A A
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 93.3 86.6 13.3 N.A. N.A. 13.3 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 93.3 100 93.3 20 N.A. N.A. 40 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 0 0 0 0 8 0 0 0 8 8 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 16 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 0 0 54 8 70 8 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 0 0 16 0 0 0 0 0 0 62 54 0 8 8 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % I
% Lys: 8 0 8 0 62 0 0 16 62 0 0 0 8 0 62 % K
% Leu: 8 8 0 0 8 0 0 0 8 0 0 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 8 8 0 0 0 8 0 0 16 % P
% Gln: 0 0 0 0 0 0 62 0 0 0 0 16 0 0 0 % Q
% Arg: 0 0 77 0 0 0 0 0 8 8 8 0 0 0 0 % R
% Ser: 62 62 0 0 0 8 8 54 0 0 8 8 62 62 0 % S
% Thr: 0 0 0 0 8 0 0 8 8 62 0 0 8 8 0 % T
% Val: 8 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _