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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 33.94
Human Site: T275 Identified Species: 62.22
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 T275 P K V S L P K T K L S L P G S
Chimpanzee Pan troglodytes XP_001138519 1992 220427 T275 P K V S L P K T K L S L P G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 T275 P K V S L P K T K L S L P G S
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 T275 P K V S L P K T K L S L P G S
Rat Rattus norvegicus NP_001026829 1976 218189 T275 P K V S L P K T K L S L P G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 T276 P K V S L P K T K L S L P G S
Chicken Gallus gallus XP_422603 1995 220955 T273 P K V S L P K T K L S L P G S
Frog Xenopus laevis NP_001084531 2027 224405 T311 P K V S L P K T K L S L P G S
Zebra Danio Brachydanio rerio XP_001919036 1688 188921 S138 T I G S G A S S K A Q Q L L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 S687 D N T S C K H S S D S I Q S E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 A359 R K S N K K L A K P A T A K Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 A275 V L P S S C A A V V H Y G A V
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 13.3 N.A. N.A. 13.3 N.A. 13.3
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 20 N.A. N.A. 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 8 16 0 8 8 0 8 8 0 % A
% Cys: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 0 0 0 0 0 0 0 8 62 0 % G
% His: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 70 0 0 8 16 62 0 77 0 0 0 0 8 0 % K
% Leu: 0 8 0 0 62 0 8 0 0 62 0 62 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 62 0 8 0 0 62 0 0 0 8 0 0 62 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 8 8 0 16 % Q
% Arg: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 8 85 8 0 8 16 8 0 70 0 0 8 62 % S
% Thr: 8 0 8 0 0 0 0 62 0 0 0 8 0 0 0 % T
% Val: 8 0 62 0 0 0 0 0 8 8 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _