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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIP12
All Species:
28.48
Human Site:
Y1104
Identified Species:
52.22
UniProt:
Q14669
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14669
NP_004229.1
1992
220434
Y1104
A
H
K
F
V
E
R
Y
F
S
S
E
N
M
D
Chimpanzee
Pan troglodytes
XP_001138519
1992
220427
Y1104
A
H
K
F
V
E
R
Y
F
S
S
E
N
M
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850221
1992
220390
Y1104
A
H
K
F
V
E
R
Y
F
S
S
E
N
M
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_598736
2025
224109
Y1137
A
H
K
F
V
E
R
Y
F
S
S
E
N
M
D
Rat
Rattus norvegicus
NP_001026829
1976
218189
H1131
G
W
I
K
E
Q
A
H
K
F
V
E
R
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505299
1999
221121
Y1111
A
H
Q
F
V
E
R
Y
F
S
S
E
N
M
D
Chicken
Gallus gallus
XP_422603
1995
220955
Y1107
A
H
K
F
V
D
R
Y
F
S
S
E
N
M
D
Frog
Xenopus laevis
NP_001084531
2027
224405
Y1144
A
H
K
F
V
D
R
Y
F
S
S
E
N
M
D
Zebra Danio
Brachydanio rerio
XP_001919036
1688
188921
S882
N
S
E
R
D
T
I
S
R
D
E
R
I
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392897
2654
295778
A1779
E
Q
A
A
Q
F
L
A
R
Y
Q
D
D
A
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783595
2536
274452
F1638
S
Q
F
I
R
Q
Y
F
S
Q
T
D
H
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q6WWW4
1888
202909
K1028
K
K
D
P
V
H
E
K
G
T
S
S
S
K
G
Baker's Yeast
Sacchar. cerevisiae
P33202
1483
167824
S676
S
V
K
P
K
K
I
S
I
H
I
F
R
T
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
99.1
N.A.
96.6
96
N.A.
95
95.1
88.5
75.8
N.A.
N.A.
40.3
N.A.
48.8
Protein Similarity:
100
99.9
N.A.
99.5
N.A.
97.3
96.6
N.A.
97.5
97.9
93.3
80.5
N.A.
N.A.
54.6
N.A.
61.8
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
93.3
93.3
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
20
N.A.
100
100
100
6.6
N.A.
N.A.
13.3
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
22.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
39.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
8
8
0
0
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
8
16
0
0
0
8
0
16
8
0
54
% D
% Glu:
8
0
8
0
8
39
8
0
0
0
8
62
0
0
0
% E
% Phe:
0
0
8
54
0
8
0
8
54
8
0
8
0
0
8
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
16
% G
% His:
0
54
0
0
0
8
0
8
0
8
0
0
8
0
0
% H
% Ile:
0
0
8
8
0
0
16
0
8
0
8
0
8
0
0
% I
% Lys:
8
8
54
8
8
8
0
8
8
0
0
0
0
16
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
54
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
54
0
0
% N
% Pro:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
16
8
0
8
16
0
0
0
8
8
0
0
8
0
% Q
% Arg:
0
0
0
8
8
0
54
0
16
0
0
8
16
0
8
% R
% Ser:
16
8
0
0
0
0
0
16
8
54
62
8
8
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
8
0
0
8
0
% T
% Val:
0
8
0
0
62
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
54
0
8
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _