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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIP12 All Species: 33.94
Human Site: Y1453 Identified Species: 62.22
UniProt: Q14669 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14669 NP_004229.1 1992 220434 Y1453 V S N P L E V Y L I P T P P E
Chimpanzee Pan troglodytes XP_001138519 1992 220427 Y1453 V S N P L E V Y L I P T P P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850221 1992 220390 Y1453 V S N P L E V Y L I S S P P E
Cat Felis silvestris
Mouse Mus musculus NP_598736 2025 224109 Y1486 V A N P L E V Y L I P T P P E
Rat Rattus norvegicus NP_001026829 1976 218189 Y1437 V A N P L E V Y L I P T P P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505299 1999 221121 Y1460 V L N P L E V Y L I S S P P E
Chicken Gallus gallus XP_422603 1995 220955 Y1456 V L N P L E V Y L I S T P P E
Frog Xenopus laevis NP_001084531 2027 224405 Y1488 I F N P L E A Y L L S G P P E
Zebra Danio Brachydanio rerio XP_001919036 1688 188921 Y1185 S R Y W F Y L Y D N A A C K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392897 2654 295778 Y2122 Q R C P L D P Y L S P T L P S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783595 2536 274452 Y1998 I Q K E L H K Y L H S N L P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q6WWW4 1888 202909 V1335 K S N S T Y N V L A L L R V L
Baker's Yeast Sacchar. cerevisiae P33202 1483 167824 D979 N E G K K L R D F Y K K R E F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 99.1 N.A. 96.6 96 N.A. 95 95.1 88.5 75.8 N.A. N.A. 40.3 N.A. 48.8
Protein Similarity: 100 99.9 N.A. 99.5 N.A. 97.3 96.6 N.A. 97.5 97.9 93.3 80.5 N.A. N.A. 54.6 N.A. 61.8
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 93.3 N.A. 80 86.6 60 13.3 N.A. N.A. 46.6 N.A. 26.6
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 86.6 86.6 73.3 20 N.A. N.A. 53.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. 23 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 39.5 N.A.
P-Site Identity: N.A. N.A. N.A. 20 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 16 0 0 0 0 8 0 0 8 8 8 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 8 0 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 62 0 0 0 0 0 0 0 8 70 % E
% Phe: 0 8 0 0 8 0 0 0 8 0 0 0 0 0 8 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % H
% Ile: 16 0 0 0 0 0 0 0 0 54 0 0 0 0 0 % I
% Lys: 8 0 8 8 8 0 8 0 0 0 8 8 0 8 0 % K
% Leu: 0 16 0 0 77 8 8 0 85 8 8 8 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 70 0 0 0 8 0 0 8 0 8 0 0 0 % N
% Pro: 0 0 0 70 0 0 8 0 0 0 39 0 62 77 0 % P
% Gln: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 16 0 0 0 0 8 0 0 0 0 0 16 0 0 % R
% Ser: 8 31 0 8 0 0 0 0 0 8 39 16 0 0 8 % S
% Thr: 0 0 0 0 8 0 0 0 0 0 0 47 0 0 0 % T
% Val: 54 0 0 0 0 0 54 8 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 16 0 85 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _