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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PUM1 All Species: 24.24
Human Site: S721 Identified Species: 59.26
UniProt: Q14671 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14671 NP_001018494.1 1186 126473 S721 S D L Y K R T S S S L T P I G
Chimpanzee Pan troglodytes XP_001157494 1154 123444 S687 S D L Y K R T S S S L T P I G
Rhesus Macaque Macaca mulatta XP_001096411 1066 113860 L654 G S S S S L N L G G L T N G S
Dog Lupus familis XP_865319 1186 126344 S721 S D L Y K R T S S S L T P I G
Cat Felis silvestris
Mouse Mus musculus Q80U78 1189 126601 S722 S D L Y K R T S S S L A P I G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2VB19 1189 126658 S722 S D L Y K R T S S S L T P I G
Frog Xenopus laevis NP_001081119 1190 127467 S723 S D I Y K R T S S S L T P I G
Zebra Danio Brachydanio rerio XP_002665632 1046 111132 P634 F S Q G S A Q P G N T S L G F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25822 1533 157510 S984 A P I T P P P S A Q S C L L G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07807 879 98049 E467 K Q A N P Y L E N S I P T K N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 89.8 99.4 N.A. 98.7 N.A. N.A. N.A. 97.6 90.3 72.5 N.A. 32.9 N.A. N.A. N.A.
Protein Similarity: 100 97.1 89.8 99.8 N.A. 99.1 N.A. N.A. N.A. 98.5 93.1 78.2 N.A. 43.8 N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 93.3 N.A. N.A. N.A. 100 93.3 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 N.A. N.A. N.A. 100 100 13.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 10 0 0 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 60 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 0 10 0 0 0 0 20 10 0 0 0 20 70 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 10 0 0 60 0 % I
% Lys: 10 0 0 0 60 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 50 0 0 10 10 10 0 0 70 0 20 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 10 0 10 10 0 0 10 0 10 % N
% Pro: 0 10 0 0 20 10 10 10 0 0 0 10 60 0 0 % P
% Gln: 0 10 10 0 0 0 10 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 60 0 0 0 0 0 0 0 0 0 % R
% Ser: 60 20 10 10 20 0 0 70 60 70 10 10 0 0 10 % S
% Thr: 0 0 0 10 0 0 60 0 0 0 10 60 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 60 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _