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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESPL1 All Species: 7.58
Human Site: T117 Identified Species: 23.81
UniProt: Q14674 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14674 NP_036423.4 2120 233113 T117 A Q G S P E V T L R L A Q P L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103494 2120 233105 T117 A Q G S P E A T L R L A Q P L
Dog Lupus familis XP_849828 2116 232497 T125 T Q G I P E A T L R F A Q P L
Cat Felis silvestris
Mouse Mus musculus P60330 2118 233016 V117 T Q G S P D T V L R L A Q P L
Rat Rattus norvegicus NP_001164073 2109 231597 V117 T Q G N P D A V L R L A Q P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423289 1597 172559
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001337869 2182 240839 A114 S L G A H G P A C R L G Q L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782226 2231 246313 D123 M D A L S F A D F L Y A E L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.9 82.3 N.A. 77.3 77.8 N.A. N.A. 27.1 N.A. 34.6 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 N.A. 97.7 88.2 N.A. 85.4 85.7 N.A. N.A. 40 N.A. 52.3 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 N.A. 93.3 73.3 N.A. 73.3 66.6 N.A. N.A. 0 N.A. 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 93.3 73.3 N.A. 80 80 N.A. N.A. 0 N.A. 46.6 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 13 13 0 0 50 13 0 0 0 75 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 25 0 13 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 38 0 0 0 0 0 0 13 0 0 % E
% Phe: 0 0 0 0 0 13 0 0 13 0 13 0 0 0 0 % F
% Gly: 0 0 75 0 0 13 0 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 13 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 0 13 0 0 0 0 63 13 63 0 0 25 63 % L
% Met: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 63 0 13 0 0 0 0 0 0 63 0 % P
% Gln: 0 63 0 0 0 0 0 0 0 0 0 0 75 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % R
% Ser: 13 0 0 38 13 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 38 0 0 0 0 0 13 38 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 13 25 0 0 0 0 0 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _