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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESPL1
All Species:
17.27
Human Site:
T456
Identified Species:
54.29
UniProt:
Q14674
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14674
NP_036423.4
2120
233113
T456
L
T
D
H
M
G
M
T
A
S
Y
T
S
N
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103494
2120
233105
T456
L
T
D
Y
I
G
M
T
A
S
Y
T
S
N
L
Dog
Lupus familis
XP_849828
2116
232497
T463
L
T
D
Y
L
G
M
T
A
S
Y
T
S
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P60330
2118
233016
T451
L
A
D
Y
L
S
M
T
A
S
Y
T
S
N
L
Rat
Rattus norvegicus
NP_001164073
2109
231597
T451
L
A
D
Y
L
G
V
T
A
S
Y
T
S
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423289
1597
172559
Q71
M
P
R
D
D
V
L
Q
L
C
A
F
V
R
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337869
2182
240839
A441
N
D
N
L
L
L
K
A
V
C
A
V
N
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782226
2231
246313
D495
R
T
K
T
V
M
E
D
V
S
K
G
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.9
82.3
N.A.
77.3
77.8
N.A.
N.A.
27.1
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
22.4
Protein Similarity:
100
N.A.
97.7
88.2
N.A.
85.4
85.7
N.A.
N.A.
40
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
40.7
P-Site Identity:
100
N.A.
86.6
86.6
N.A.
73.3
73.3
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
N.A.
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
0
0
0
0
0
13
63
0
25
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% C
% Asp:
0
13
63
13
13
0
0
13
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
13
13
13
25
% G
% His:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
13
0
0
0
13
0
0
0
0
% K
% Leu:
63
0
0
13
50
13
13
0
13
0
0
0
0
0
63
% L
% Met:
13
0
0
0
13
13
50
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
13
0
0
0
0
0
0
0
0
0
13
75
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% Q
% Arg:
13
0
13
0
0
0
0
0
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
13
0
0
0
75
0
0
63
0
0
% S
% Thr:
0
50
0
13
0
0
0
63
0
0
0
63
0
0
0
% T
% Val:
0
0
0
0
13
13
13
0
25
0
0
13
13
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
50
0
0
0
0
0
0
63
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _