KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL4
All Species:
14.55
Human Site:
S299
Identified Species:
32
UniProt:
Q14679
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14679
NP_055455.3
1199
133378
S299
S
H
D
T
S
T
T
S
V
A
S
S
W
Y
N
Chimpanzee
Pan troglodytes
XP_516095
1199
133350
S299
S
H
D
T
S
T
T
S
V
A
S
S
W
Y
N
Rhesus Macaque
Macaca mulatta
XP_001094742
1199
133368
S299
S
H
D
T
S
T
T
S
V
A
S
S
W
Y
N
Dog
Lupus familis
XP_545645
1200
132528
S299
S
L
D
T
L
T
T
S
V
A
S
P
Q
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q80UG8
1193
132512
T299
N
I
S
T
A
S
V
T
S
S
Q
C
S
Q
S
Rat
Rattus norvegicus
XP_001074653
1198
133072
V299
L
N
I
S
T
A
S
V
A
S
S
Q
C
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422058
698
79620
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001098408
578
66246
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722946
989
111378
P131
V
S
A
R
Y
S
P
P
G
Q
K
Q
R
S
P
Honey Bee
Apis mellifera
XP_396662
612
72107
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177836
814
91837
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.3
84
N.A.
80.4
80.9
N.A.
N.A.
43.9
N.A.
34.1
N.A.
29.4
25.6
N.A.
33.2
Protein Similarity:
100
99.6
97.7
87.1
N.A.
86.9
87.9
N.A.
N.A.
51.1
N.A.
40.2
N.A.
46.2
36.2
N.A.
47.4
P-Site Identity:
100
100
100
73.3
N.A.
6.6
6.6
N.A.
N.A.
0
N.A.
0
N.A.
0
0
N.A.
0
P-Site Similarity:
100
100
100
73.3
N.A.
46.6
40
N.A.
N.A.
0
N.A.
0
N.A.
6.6
0
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
10
0
0
10
37
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
10
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
37
% N
% Pro:
0
0
0
0
0
0
10
10
0
0
0
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
10
19
10
10
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
37
10
10
10
28
19
10
37
10
19
46
28
10
19
10
% S
% Thr:
0
0
0
46
10
37
37
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
10
37
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
37
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _