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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL4
All Species:
13.64
Human Site:
T416
Identified Species:
30
UniProt:
Q14679
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14679
NP_055455.3
1199
133378
T416
L
D
N
T
V
F
C
T
K
R
I
S
I
H
L
Chimpanzee
Pan troglodytes
XP_516095
1199
133350
T416
L
D
N
T
V
F
C
T
K
R
I
S
I
H
L
Rhesus Macaque
Macaca mulatta
XP_001094742
1199
133368
T416
L
D
N
T
V
F
C
T
K
R
I
S
I
H
L
Dog
Lupus familis
XP_545645
1200
132528
K417
D
G
T
V
F
C
T
K
R
I
S
I
H
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80UG8
1193
132512
T411
L
D
S
T
V
F
C
T
K
R
I
S
I
H
L
Rat
Rattus norvegicus
XP_001074653
1198
133072
R414
S
T
V
F
C
T
K
R
I
S
I
H
L
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422058
698
79620
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001098408
578
66246
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722946
989
111378
A242
A
H
S
P
P
I
Q
A
K
V
P
P
S
N
M
Honey Bee
Apis mellifera
XP_396662
612
72107
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177836
814
91837
V67
I
K
Q
P
T
N
K
V
T
G
N
N
R
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.3
84
N.A.
80.4
80.9
N.A.
N.A.
43.9
N.A.
34.1
N.A.
29.4
25.6
N.A.
33.2
Protein Similarity:
100
99.6
97.7
87.1
N.A.
86.9
87.9
N.A.
N.A.
51.1
N.A.
40.2
N.A.
46.2
36.2
N.A.
47.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
6.6
N.A.
N.A.
0
N.A.
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
13.3
N.A.
N.A.
0
N.A.
0
N.A.
26.6
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
10
10
37
0
0
0
0
0
0
0
0
% C
% Asp:
10
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
10
10
37
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
10
10
37
0
% H
% Ile:
10
0
0
0
0
10
0
0
10
10
46
10
37
0
0
% I
% Lys:
0
10
0
0
0
0
19
10
46
0
0
0
0
0
0
% K
% Leu:
37
0
0
0
0
0
0
0
0
0
0
0
10
19
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
28
0
0
10
0
0
0
0
10
10
0
10
10
% N
% Pro:
0
0
0
19
10
0
0
0
0
0
10
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
10
37
0
0
10
0
0
% R
% Ser:
10
0
19
0
0
0
0
0
0
10
10
37
10
10
0
% S
% Thr:
0
10
10
37
10
10
10
37
10
0
0
0
0
0
0
% T
% Val:
0
0
10
10
37
0
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _