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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTLL4
All Species:
17.58
Human Site:
T586
Identified Species:
38.67
UniProt:
Q14679
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14679
NP_055455.3
1199
133378
T586
L
F
P
N
V
P
P
T
I
Y
F
G
T
R
D
Chimpanzee
Pan troglodytes
XP_516095
1199
133350
T586
L
F
P
N
V
P
P
T
I
Y
F
G
T
R
D
Rhesus Macaque
Macaca mulatta
XP_001094742
1199
133368
T586
L
F
P
N
V
P
P
T
I
Y
F
G
T
R
D
Dog
Lupus familis
XP_545645
1200
132528
I587
F
P
N
V
P
P
T
I
Y
F
G
T
R
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80UG8
1193
132512
T581
L
F
P
N
V
T
P
T
I
Y
F
G
T
R
D
Rat
Rattus norvegicus
XP_001074653
1198
133072
T584
L
F
P
N
V
S
P
T
I
Y
F
G
T
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422058
698
79620
L121
E
E
E
L
P
D
G
L
D
E
S
C
S
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001098408
578
66246
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722946
989
111378
D412
K
E
S
V
R
T
T
D
S
E
A
S
V
Y
F
Honey Bee
Apis mellifera
XP_396662
612
72107
L34
S
V
E
L
K
P
N
L
F
H
H
R
C
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177836
814
91837
A237
E
R
L
P
A
D
G
A
S
Y
D
D
F
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
96.3
84
N.A.
80.4
80.9
N.A.
N.A.
43.9
N.A.
34.1
N.A.
29.4
25.6
N.A.
33.2
Protein Similarity:
100
99.6
97.7
87.1
N.A.
86.9
87.9
N.A.
N.A.
51.1
N.A.
40.2
N.A.
46.2
36.2
N.A.
47.4
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
N.A.
0
N.A.
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
0
N.A.
0
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
0
0
0
0
0
19
0
10
10
0
10
10
0
19
46
% D
% Glu:
19
19
19
0
0
0
0
0
0
19
0
0
0
0
28
% E
% Phe:
10
46
0
0
0
0
0
0
10
10
46
0
10
0
10
% F
% Gly:
0
0
0
0
0
0
19
0
0
0
10
46
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
46
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
46
0
10
19
0
0
0
19
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
46
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
46
10
19
46
46
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
10
0
0
0
0
0
0
10
10
46
10
% R
% Ser:
10
0
10
0
0
10
0
0
19
0
10
10
10
0
0
% S
% Thr:
0
0
0
0
0
19
19
46
0
0
0
10
46
0
0
% T
% Val:
0
10
0
19
46
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
55
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _