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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
50.61
Human Site:
S161
Identified Species:
74.22
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
S161
F
F
E
E
I
S
S
S
G
E
L
I
G
E
Y
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Dog
Lupus familis
XP_538049
1295
149661
S223
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
K145
D
Y
E
A
K
K
K
K
V
Q
K
A
E
E
D
Chicken
Gallus gallus
Q90988
1189
134923
T180
M
Y
E
C
K
K
I
T
A
H
K
T
I
E
K
Frog
Xenopus laevis
O93308
1232
142609
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
S161
L
F
E
E
I
S
R
S
G
E
L
A
Q
E
Y
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
S161
M
F
E
S
I
S
Q
S
K
E
L
A
A
E
Y
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
S184
L
F
E
E
I
S
G
S
G
L
L
K
D
D
Y
Honey Bee
Apis mellifera
XP_395059
1230
141414
S162
L
F
E
E
I
S
N
S
G
A
L
K
A
E
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S161
L
F
E
E
I
S
R
S
G
E
L
R
E
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
Y195
H
D
E
G
F
L
E
Y
L
E
D
I
I
G
T
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
S175
M
F
E
E
V
S
G
S
I
Q
Y
K
K
E
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
20
13.3
100
100
66.6
66.6
73.3
N.A.
86.6
P-Site Similarity:
100
73.3
100
100
N.A.
100
100
N.A.
46.6
33.3
100
100
80
73.3
73.3
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
0
7
7
0
57
13
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
0
0
0
7
0
7
7
7
% D
% Glu:
0
0
100
75
0
0
7
0
0
69
0
0
13
88
0
% E
% Phe:
7
82
0
0
7
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
13
0
69
0
0
0
7
7
0
% G
% His:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
75
0
7
0
7
0
0
13
13
0
0
% I
% Lys:
0
0
0
0
13
13
7
7
7
0
13
19
7
0
7
% K
% Leu:
63
0
0
0
0
7
0
0
7
7
75
0
0
0
0
% L
% Met:
19
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
13
0
0
44
0
0
% Q
% Arg:
0
0
0
0
0
0
50
0
0
0
0
7
0
0
0
% R
% Ser:
0
0
0
7
0
82
7
82
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
7
% T
% Val:
0
0
0
0
7
0
0
0
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
7
0
0
7
0
0
0
82
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _