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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
25.45
Human Site:
S970
Identified Species:
37.33
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
S970
V
S
G
S
Q
R
I
S
S
I
Y
A
R
E
A
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
E970
Q
A
T
I
D
I
Y
E
K
E
E
A
F
E
I
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
S966
G
E
D
S
V
S
G
S
Q
R
I
S
S
I
Y
Dog
Lupus familis
XP_538049
1295
149661
S1032
V
S
G
S
Q
R
T
S
S
I
Y
A
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
S970
V
S
G
S
Q
R
T
S
S
I
Y
A
R
E
A
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
S970
V
S
G
S
Q
R
T
S
S
I
Y
A
R
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
E941
Q
A
T
S
V
I
F
E
R
E
A
A
I
E
I
Chicken
Gallus gallus
Q90988
1189
134923
Y938
L
D
K
L
L
K
E
Y
K
W
I
A
S
E
K
Frog
Xenopus laevis
O93308
1232
142609
S970
A
S
S
S
Q
R
S
S
T
V
Y
A
K
E
A
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
S970
I
S
S
P
K
A
S
S
S
V
H
A
K
E
A
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
Y976
T
L
G
T
L
D
L
Y
E
R
E
A
L
L
I
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
N990
S
T
S
A
A
M
E
N
I
I
E
V
D
Y
S
Honey Bee
Apis mellifera
XP_395059
1230
141414
T972
N
N
D
S
S
L
N
T
Q
Q
Q
Y
E
R
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
T970
A
D
D
M
E
S
M
T
G
A
D
S
M
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
V1000
E
Q
I
Q
K
D
L
V
D
P
D
K
L
Q
A
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
N969
L
P
I
S
S
T
D
N
E
A
I
T
I
S
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
13.3
13.3
93.3
N.A.
93.3
93.3
N.A.
20
13.3
60
40
13.3
6.6
6.6
N.A.
0
P-Site Similarity:
100
20
20
93.3
N.A.
93.3
93.3
N.A.
26.6
26.6
80
73.3
26.6
33.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
13
0
7
7
7
0
0
0
13
7
63
0
0
44
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
19
0
7
13
7
0
7
0
13
0
7
0
0
% D
% Glu:
7
7
0
0
7
0
13
13
13
13
19
0
7
57
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
7
0
32
0
0
0
7
0
7
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
13
7
0
13
7
0
7
32
19
0
13
7
19
% I
% Lys:
0
0
7
0
13
7
0
0
13
0
0
7
13
0
7
% K
% Leu:
13
7
0
7
13
7
13
0
0
0
0
0
13
7
0
% L
% Met:
0
0
0
7
0
7
7
0
0
0
0
0
7
0
0
% M
% Asn:
7
7
0
0
0
0
7
13
0
0
0
0
0
0
7
% N
% Pro:
0
7
0
7
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
13
7
0
7
32
0
0
0
13
7
7
0
0
7
0
% Q
% Arg:
0
0
0
0
0
32
0
0
7
13
0
0
25
7
0
% R
% Ser:
7
38
19
57
13
13
13
44
32
0
0
13
13
13
13
% S
% Thr:
7
7
13
7
0
7
19
13
7
0
0
7
0
0
0
% T
% Val:
25
0
0
0
13
0
0
7
0
13
0
7
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
13
0
0
32
7
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _