KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
39.39
Human Site:
T638
Identified Species:
57.78
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
T638
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
T638
S
G
P
E
R
Q
K
T
V
A
L
D
G
T
L
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
T638
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Dog
Lupus familis
XP_538049
1295
149661
T700
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
T638
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T638
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
T609
H
G
P
E
R
L
K
T
V
A
L
D
G
T
L
Chicken
Gallus gallus
Q90988
1189
134923
T649
D
K
R
I
M
R
K
T
V
T
L
Q
G
D
I
Frog
Xenopus laevis
O93308
1232
142609
T638
G
G
H
Q
R
H
K
T
V
A
L
D
G
T
L
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
T638
G
G
P
Y
R
H
K
T
V
A
L
D
G
T
L
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
T646
D
R
P
E
R
H
K
T
V
S
L
D
G
T
L
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
A664
I
D
R
S
R
F
D
A
L
A
L
D
G
T
F
Honey Bee
Apis mellifera
XP_395059
1230
141414
C643
D
K
K
A
R
Y
D
C
V
A
L
D
G
T
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
A640
G
R
Y
E
R
H
K
A
V
A
L
D
G
T
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
V681
G
N
R
E
F
R
R
V
V
A
L
D
G
A
L
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
L651
K
K
G
I
R
G
K
L
V
T
I
E
G
A
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
73.3
33.3
100
86.6
66.6
40
46.6
N.A.
66.6
P-Site Similarity:
100
80
100
100
N.A.
100
100
N.A.
80
40
100
86.6
80
46.6
53.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
0
0
13
0
82
0
0
0
13
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
19
7
0
0
0
0
13
0
0
0
0
88
0
7
0
% D
% Glu:
0
0
0
32
0
0
0
0
0
0
0
7
0
0
0
% E
% Phe:
0
0
0
0
7
7
0
0
0
0
0
0
0
0
13
% F
% Gly:
57
57
7
0
0
7
0
0
0
0
0
0
100
0
0
% G
% His:
7
0
38
0
0
57
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
13
0
0
0
0
0
0
7
0
0
0
7
% I
% Lys:
7
19
7
0
0
0
82
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
7
0
7
7
0
94
0
0
0
75
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
38
0
7
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
13
19
0
88
13
7
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
69
0
13
0
0
0
82
0
% T
% Val:
0
0
0
0
0
0
0
7
94
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _