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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
42.12
Human Site:
T815
Identified Species:
61.78
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
T815
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
T815
L
E
F
E
K
Q
K
T
R
L
N
V
Q
L
E
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
T815
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Dog
Lupus familis
XP_538049
1295
149661
T877
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
T815
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
T815
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
T786
L
E
F
E
K
Q
K
T
R
L
S
V
Q
L
E
Chicken
Gallus gallus
Q90988
1189
134923
A783
L
E
N
K
M
K
N
A
E
A
E
R
G
K
E
Frog
Xenopus laevis
O93308
1232
142609
T815
L
E
F
E
N
Q
K
T
R
L
G
I
Q
L
D
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
T815
L
E
F
E
T
Q
K
T
R
L
A
I
Q
L
D
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
T823
L
E
F
E
S
H
R
T
R
L
N
A
Q
L
E
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
D840
A
E
F
E
Q
Q
I
D
S
I
N
S
Q
L
D
Honey Bee
Apis mellifera
XP_395059
1230
141414
N819
M
E
F
E
N
Q
C
N
R
I
Y
N
Q
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
S817
L
E
F
E
N
Q
K
S
R
L
A
N
Q
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
L825
L
E
K
G
S
K
Q
L
K
D
K
L
Q
T
N
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
D775
D
D
L
E
N
T
K
D
N
L
V
K
E
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
73.3
13.3
100
86.6
60
46.6
60
N.A.
73.3
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
86.6
33.3
100
86.6
80
53.3
73.3
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
0
7
13
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
0
0
0
0
0
13
0
7
0
0
0
0
57
% D
% Glu:
0
94
0
88
0
0
0
0
7
0
7
0
7
0
38
% E
% Phe:
0
0
82
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
38
0
7
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
13
0
44
0
0
0
% I
% Lys:
0
0
7
7
13
13
69
0
7
0
7
7
0
13
0
% K
% Leu:
82
0
7
0
0
0
0
7
0
75
0
7
0
82
0
% L
% Met:
7
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
57
0
7
7
7
0
19
13
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
75
7
0
0
0
0
0
88
0
0
% Q
% Arg:
0
0
0
0
0
0
7
0
75
0
0
7
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
7
7
0
7
7
0
0
0
% S
% Thr:
0
0
0
0
7
7
0
63
0
0
0
0
0
7
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
7
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _