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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMC1A
All Species:
44.85
Human Site:
Y1113
Identified Species:
65.78
UniProt:
Q14683
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14683
NP_006297.2
1233
143233
Y1113
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Chimpanzee
Pan troglodytes
XP_515195
1235
143766
Y1109
P
Y
L
E
G
I
S
Y
N
C
V
A
P
G
K
Rhesus Macaque
Macaca mulatta
XP_001091228
1196
139006
N1080
C
F
E
S
V
A
T
N
I
D
E
I
Y
K
A
Dog
Lupus familis
XP_538049
1295
149661
Y1175
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CU62
1233
143197
Y1113
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Rat
Rattus norvegicus
Q9Z1M9
1233
143186
Y1113
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511311
1329
152821
Y1080
P
Y
L
E
G
I
S
Y
N
C
V
A
P
G
K
Chicken
Gallus gallus
Q90988
1189
134923
F1070
N
I
L
D
G
L
E
F
R
V
G
L
G
D
I
Frog
Xenopus laevis
O93308
1232
142609
Y1113
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Zebra Danio
Brachydanio rerio
NP_001155103
1232
143125
Y1113
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Tiger Blowfish
Takifugu rubipres
NP_001027867
1245
142913
Y1116
P
F
L
G
G
I
N
Y
C
C
V
A
P
G
K
Fruit Fly
Dros. melanogaster
NP_651211
1238
142862
I1111
N
E
A
A
Q
A
Y
I
G
P
D
N
P
E
E
Honey Bee
Apis mellifera
XP_395059
1230
141414
Y1115
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786064
1247
143265
Y1123
P
Y
L
D
G
I
N
Y
N
C
V
A
P
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
F1127
P
F
S
E
G
V
V
F
S
V
R
P
P
K
K
Baker's Yeast
Sacchar. cerevisiae
P32908
1225
141262
P1107
T
I
E
D
E
D
E
P
F
N
A
G
I
K
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.3
97
95.1
N.A.
99.4
99.5
N.A.
48.9
25.1
93.8
89.1
46.9
49
54.7
N.A.
62.7
Protein Similarity:
100
74.6
97
95.1
N.A.
99.8
99.6
N.A.
68.1
46.7
96.5
95.4
70.2
70.3
73.6
N.A.
79.9
P-Site Identity:
100
86.6
0
100
N.A.
100
100
N.A.
86.6
20
100
100
80
6.6
100
N.A.
100
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
100
33.3
100
100
86.6
13.3
100
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.6
30.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
57
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
0
13
0
0
0
0
7
69
0
0
7
% A
% Cys:
7
0
0
0
0
0
0
0
7
69
0
0
0
0
0
% C
% Asp:
0
0
0
63
0
7
0
0
0
7
7
0
0
7
0
% D
% Glu:
0
7
13
19
7
0
13
0
0
0
7
0
0
7
7
% E
% Phe:
0
19
0
0
0
0
0
13
7
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
82
0
0
0
7
0
7
7
7
69
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
69
0
7
7
0
0
7
7
0
7
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
75
% K
% Leu:
0
0
75
0
0
7
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
13
0
0
0
0
0
57
7
63
7
0
7
0
0
0
% N
% Pro:
75
0
0
0
0
0
0
7
0
7
0
7
82
0
0
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% R
% Ser:
0
0
7
7
0
0
13
0
7
0
0
0
0
0
0
% S
% Thr:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
7
7
7
0
0
13
69
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
63
0
0
0
0
7
69
0
0
0
0
7
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _