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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRP1B
All Species:
7.58
Human Site:
S278
Identified Species:
16.67
UniProt:
Q14684
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14684
NP_055871.1
758
84411
S278
H
S
R
K
D
G
L
S
D
E
R
G
R
D
D
Chimpanzee
Pan troglodytes
XP_001144331
758
84400
S278
H
S
R
K
D
G
L
S
D
E
R
G
R
D
D
Rhesus Macaque
Macaca mulatta
XP_001104749
757
84489
T278
S
S
R
G
G
F
I
T
E
S
R
S
V
A
Q
Dog
Lupus familis
XP_535600
705
78213
R251
G
V
H
G
D
G
E
R
G
G
G
R
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91YK2
724
80564
R267
A
A
L
D
E
C
L
R
D
G
V
I
G
S
R
Rat
Rattus norvegicus
XP_228076
733
81457
I271
E
C
L
R
D
G
V
I
G
S
R
E
R
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511992
745
81602
S269
K
G
R
S
A
Q
S
S
P
K
E
P
K
V
Q
Chicken
Gallus gallus
NP_001026505
755
84389
V279
S
A
E
K
T
E
D
V
D
E
N
A
D
D
S
Frog
Xenopus laevis
NP_001079701
613
69077
L163
T
L
G
V
Q
L
H
L
I
D
I
Y
L
E
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJZ7
687
78978
K237
I
A
T
Q
R
D
A
K
L
V
A
Q
C
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798604
679
76515
V229
R
V
Y
D
L
G
L
V
R
V
G
G
G
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
87.7
66.3
N.A.
61.6
64.1
N.A.
53.1
47
39.7
N.A.
N.A.
24.4
N.A.
N.A.
26.6
Protein Similarity:
100
99.7
90.2
75
N.A.
74
76.1
N.A.
68
65.1
55.1
N.A.
N.A.
40.2
N.A.
N.A.
43.4
P-Site Identity:
100
100
20
20
N.A.
13.3
33.3
N.A.
13.3
26.6
0
N.A.
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
40
26.6
N.A.
26.6
46.6
N.A.
26.6
33.3
20
N.A.
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
0
10
0
10
0
0
0
10
10
0
10
0
% A
% Cys:
0
10
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
19
37
10
10
0
37
10
0
0
10
37
28
% D
% Glu:
10
0
10
0
10
10
10
0
10
28
10
10
0
19
10
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
19
10
46
0
0
19
19
19
28
19
0
0
% G
% His:
19
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
10
10
0
10
10
0
10
10
% I
% Lys:
10
0
0
28
0
0
0
10
0
10
0
0
10
0
0
% K
% Leu:
0
10
19
0
10
10
37
10
10
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% P
% Gln:
0
0
0
10
10
10
0
0
0
0
0
10
0
0
19
% Q
% Arg:
10
0
37
10
10
0
0
19
10
0
37
10
28
10
10
% R
% Ser:
19
28
0
10
0
0
10
28
0
19
0
10
0
10
10
% S
% Thr:
10
0
10
0
10
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
19
0
10
0
0
10
19
0
19
10
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _