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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRP1B All Species: 12.12
Human Site: S505 Identified Species: 26.67
UniProt: Q14684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14684 NP_055871.1 758 84411 S505 S Q S G P S G S H P Q G P R G
Chimpanzee Pan troglodytes XP_001144331 758 84400 S505 S Q S G P S G S H P Q G P R G
Rhesus Macaque Macaca mulatta XP_001104749 757 84489 S505 S Q S G P S G S H P Q G P R G
Dog Lupus familis XP_535600 705 78213 E460 S T A L P P L E D A A P G G P
Cat Felis silvestris
Mouse Mus musculus Q91YK2 724 80564 S477 T L P Q E D M S K N D A V S G
Rat Rattus norvegicus XP_228076 733 81457 T482 R E I W K S T T L P Q E D V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511992 745 81602 A498 S A L A N G A A Q E P V P N R
Chicken Gallus gallus NP_001026505 755 84389 A506 C Q N G P A N A K K A E D V N
Frog Xenopus laevis NP_001079701 613 69077 K372 E E K R E K R K R A A V A P N
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJZ7 687 78978 Y446 E L Q K K V N Y N A K V R S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798604 679 76515 F438 G D A E A E T F P S P T G A S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 87.7 66.3 N.A. 61.6 64.1 N.A. 53.1 47 39.7 N.A. N.A. 24.4 N.A. N.A. 26.6
Protein Similarity: 100 99.7 90.2 75 N.A. 74 76.1 N.A. 68 65.1 55.1 N.A. N.A. 40.2 N.A. N.A. 43.4
P-Site Identity: 100 100 100 13.3 N.A. 13.3 20 N.A. 13.3 20 0 N.A. N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 20 33.3 N.A. 20 40 6.6 N.A. N.A. 13.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 10 10 10 10 19 0 28 28 10 10 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 10 0 0 10 0 10 0 19 0 0 % D
% Glu: 19 19 0 10 19 10 0 10 0 10 0 19 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 37 0 10 28 0 0 0 0 28 19 10 37 % G
% His: 0 0 0 0 0 0 0 0 28 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 19 10 0 10 19 10 10 0 0 0 0 % K
% Leu: 0 19 10 10 0 0 10 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 19 0 10 10 0 0 0 10 19 % N
% Pro: 0 0 10 0 46 10 0 0 10 37 19 10 37 10 10 % P
% Gln: 0 37 10 10 0 0 0 0 10 0 37 0 0 0 0 % Q
% Arg: 10 0 0 10 0 0 10 0 10 0 0 0 10 28 10 % R
% Ser: 46 0 28 0 0 37 0 37 0 10 0 0 0 19 28 % S
% Thr: 10 10 0 0 0 0 19 10 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 10 0 0 0 0 0 28 10 19 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _