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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRP1B All Species: 11.21
Human Site: S640 Identified Species: 24.67
UniProt: Q14684 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14684 NP_055871.1 758 84411 S640 K Q K L R A E S D F V K F D T
Chimpanzee Pan troglodytes XP_001144331 758 84400 S640 K Q K L R A E S D F V K F D T
Rhesus Macaque Macaca mulatta XP_001104749 757 84489 R639 R Q K K K K N R A C S Q Q P S
Dog Lupus familis XP_535600 705 78213 F589 Q L R T E N D F V R F D T A F
Cat Felis silvestris
Mouse Mus musculus Q91YK2 724 80564 D606 K K P L K T E D D F V K F D T
Rat Rattus norvegicus XP_228076 733 81457 D615 K K P L K M E D D L V K F D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511992 745 81602 T628 A K K A K L K T E N D F V K F
Chicken Gallus gallus NP_001026505 755 84389 S639 K K K A K Q G S D F V K F E K
Frog Xenopus laevis NP_001079701 613 69077 T501 M S C T T P E T E E R F I A G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJZ7 687 78978 W575 D D A P T N G W D A P L E D G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798604 679 76515 T567 A A F E K V S T P P A Y V K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 87.7 66.3 N.A. 61.6 64.1 N.A. 53.1 47 39.7 N.A. N.A. 24.4 N.A. N.A. 26.6
Protein Similarity: 100 99.7 90.2 75 N.A. 74 76.1 N.A. 68 65.1 55.1 N.A. N.A. 40.2 N.A. N.A. 43.4
P-Site Identity: 100 100 13.3 0 N.A. 66.6 60 N.A. 6.6 53.3 6.6 N.A. N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 40 20 N.A. 80 73.3 N.A. 40 73.3 20 N.A. N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 10 19 0 19 0 0 10 10 10 0 0 19 0 % A
% Cys: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 10 10 0 0 0 0 10 19 55 0 10 10 0 46 0 % D
% Glu: 0 0 0 10 10 0 46 0 19 10 0 0 10 10 0 % E
% Phe: 0 0 10 0 0 0 0 10 0 37 10 19 46 0 19 % F
% Gly: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 19 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 46 37 46 10 55 10 10 0 0 0 0 46 0 19 19 % K
% Leu: 0 10 0 37 0 10 0 0 0 10 0 10 0 0 0 % L
% Met: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 19 10 0 0 10 0 0 0 0 0 % N
% Pro: 0 0 19 10 0 10 0 0 10 10 10 0 0 10 0 % P
% Gln: 10 28 0 0 0 10 0 0 0 0 0 10 10 0 0 % Q
% Arg: 10 0 10 0 19 0 0 10 0 10 10 0 0 0 0 % R
% Ser: 0 10 0 0 0 0 10 28 0 0 10 0 0 0 10 % S
% Thr: 0 0 0 19 19 10 0 28 0 0 0 0 10 0 37 % T
% Val: 0 0 0 0 0 10 0 0 10 0 46 0 19 0 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _